Murata M, Takayama K, Fukuma S, Okamoto N, Kato I, Hanai A, Nakayama H, Fujiwara K, Ikeda T, Fujimoto I
Division of Epidemiology, Chiba Cancer Center.
Jpn J Cancer Res. 1988 Sep;79(9):1005-16. doi: 10.1111/j.1349-7006.1988.tb00067.x.
To examine what kinds of factors could have caused the geographic variation observed in lung cancer morbidity in Japan, a correlation study was performed comparing various regional traits. The same study was also conducted on large intestinal cancer, aiming to distinguish the possible urban factors associated with both cancers. Lung cancer was highly correlated with industrialization-related factors such as localization of manufacturing industries, automobile traffic and air pollution, whereas colon cancer was correlated with the population density of workers in the tertiary industries such as services, trade and government. A multiple regression analysis could not detect any single factor with an exceptionally strong influence on either cancer. The present findings suggest that the hazardous environmental condition of urban areas has, to some extent, contributed to the recent increase of lung cancer cases in this country.
为了研究哪些因素可能导致了日本肺癌发病率存在的地域差异，开展了一项相关性研究，比较了不同的区域特征。同时也对大肠癌进行了同样的研究，旨在区分与这两种癌症可能相关的城市因素。肺癌与工业化相关因素高度相关，如制造业的分布、汽车交通和空气污染，而结肠癌则与服务业、贸易和政府等第三产业工人的人口密度相关。多元回归分析未发现对任何一种癌症有特别强烈影响的单一因素。目前的研究结果表明，城市地区有害的环境状况在一定程度上导致了该国近期肺癌病例的增加。
