评估水疗对退行性关节和椎间盘疾病患者脂代谢变化的影响。
Assessment of Changes in Lipids Metabolism in Patients with Degenerative Joints and Discs Diseases Subjected to Spa Therapy.
机构信息
Department of Physiotherapy, Medical University of Wroclaw, Poland.
出版信息
Biomed Res Int. 2019 Jul 24;2019:4732654. doi: 10.1155/2019/4732654. eCollection 2019.
INTRODUCTION
High levels of total cholesterol, triglycerides, and, connected with them, lipoprotein fractions may result in atherosclerosis. There are various forms of therapy used to prevent cardiovascular diseases, such as balneophysiotherapy, the effectiveness of which is confirmed by numerous scientific publications.
OBJECTIVE
The objective of this study was to assess the impact of balneophysiotherapeutic procedures on the systemic metabolism of lipids in patients suffering from osteoarthritis of the motor organ.
MATERIAL AND METHODS
The study was conducted in the Health Resort Świeradów-Zdrój. Observation included patients undergoing radon water therapy. Before therapy and after 21 days of treatment, lipid profile was assessed with the use of standard colorimetric assay. Study group consisted of n=34 patients with degenerative joints and disc disease. The mean age of patients was 56.5l. The control group consisted of 17 people selected among the employees of the spa also suffering from osteoarthritis. The mean age was 54.2 years.
RESULTS
The results of the study are based on a single, 21-day health resort stay period in April/May. A statistically significant increase in HDL cholesterol levels was observed in female patients having undergone health resort treatment (<0.01). Statistically significant drops in LDL cholesterol and TG levels were observed in the control group (<0.01). An increase in HDL levels was observed in the male and female control subjects, with <0.05.
CONCLUSIONS
(1) After the end of therapy, there were no changes in lipid metabolism in men, while in the group of women an increase in HDL level was observed. (2) In the control group, statistically significant changes in the field of lipid metabolism may be related to lifestyle changes as a result of educational activities conducted prior to the research. (3) Due to the divergent results, it is advisable to conduct randomized studies in a larger population. This trial is registered with NCT03274128.
简介
总胆固醇、甘油三酯水平升高，以及与之相关的脂蛋白亚类水平升高，可能导致动脉粥样硬化。有多种治疗方法可用于预防心血管疾病，如矿泉浴物理疗法，其有效性已被众多科学出版物所证实。
目的
本研究旨在评估矿泉浴物理疗法对患有运动器官骨关节炎患者全身脂质代谢的影响。
材料和方法
该研究在斯维德尼克温泉疗养地进行。观察对象接受氡水疗法。在治疗前和治疗 21 天后，使用标准比色法评估血脂谱。研究组包括 n=34 例退行性关节和椎间盘疾病患者。患者平均年龄为 56.5 岁。对照组由 17 名在温泉疗养地工作的、患有骨关节炎的人员组成。平均年龄为 54.2 岁。
结果
该研究的结果基于 4 月/5 月为期 21 天的单一温泉疗养期。接受温泉治疗的女性患者的 HDL 胆固醇水平显著升高（<0.01）。对照组的 LDL 胆固醇和 TG 水平显著下降（<0.01）。男性和女性对照组的 HDL 水平也有所升高，差异具有统计学意义（<0.05）。
结论
（1）治疗结束后，男性的脂质代谢没有变化，而女性的 HDL 水平升高。（2）对照组脂质代谢领域的显著变化可能与研究前开展的教育活动导致的生活方式改变有关。（3）由于结果存在差异，建议在更大的人群中进行随机研究。本试验已在 NCT03274128 注册。
Zotero 插件