Najafian Jamshid, Nouri Fatemeh, Mohammadifard Nooshin
Associate Professor, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
ARYA Atheroscler. 2019 Jan;15(1):22-26. doi: 10.22122/arya.v15i1.1657.
Hypertension (HTN) is an important risk factor for atherosclerotic and non-atherosclerotic cardiovascular disease (CVD). HTN increases risk of stroke and diabetes complications and at the end stage renal disease. Sleep disorders including short sleep duration are involved in pathogenesis of HTN. This study aimed to examine the association between self-reported sleep duration and HTN in a group of adult population in Isfahan City, Iran.
This cross-sectional survey was performed as part of the Isfahan Healthy Heart Program (IHHP). A total of 12492 individuals aged over 19 years (6110 men and 6382 women) entered the study. Sleep duration was recorded according to subjects' self-report. HTN was defined as a systolic blood pressure (SBP) of ≥ 140 mmHg, a diastolic blood pressure (DBP) of ≥ 90 mmHg, or use of antihypertensive medication. The relation between sleep hours and HTN was examined using multiple logistic regression in three models, unadjusted, adjusted according to age and sex, and adjusted according to age, sex, body mass index (BMI), and waist circumference (WC).
Sleeping time less than 5 hours, in comparison to sleep duration of 7-8 hours per night,was associated with a higher risk of HTN [odds ratio (OR) = 2.52, 95% confidence interval (CI): 2.17-2.93]. This association remained significant even after adjustment for age, sex, BMI, and WC (OR = 1.38, 95% CI: 1.16-1.64). Sleep duration over 9 hours had a negative association with risk of HTN among those under 60 years old (OR = 0.63, 95% CI: 0.47-0.86).
Sleep duration less than 5 hours is positively associated with HTN. It seems that sleep duration might affect HTN and atherosclerotic CVD.
高血压（HTN）是动脉粥样硬化性和非动脉粥样硬化性心血管疾病（CVD）的重要危险因素。高血压会增加中风、糖尿病并发症以及终末期肾病的风险。包括睡眠时间短在内的睡眠障碍参与了高血压的发病机制。本研究旨在调查伊朗伊斯法罕市一组成年人群中自我报告的睡眠时间与高血压之间的关联。
这项横断面调查是伊斯法罕健康心脏项目（IHHP）的一部分。共有12492名19岁以上的个体（6110名男性和6382名女性）进入研究。睡眠时间根据受试者的自我报告进行记录。高血压定义为收缩压（SBP）≥140 mmHg、舒张压（DBP）≥90 mmHg或使用抗高血压药物。在三个模型中使用多元逻辑回归分析睡眠时间与高血压之间的关系，即未调整模型、根据年龄和性别调整的模型以及根据年龄、性别、体重指数（BMI）和腰围（WC）调整的模型。
与每晚睡眠7 - 8小时相比，睡眠时间少于5小时与高血压风险更高相关[比值比（OR）= 2.52，95%置信区间（CI）：2.17 - 2.93]。即使在调整年龄、性别、BMI和WC后，这种关联仍然显著（OR = 1.38，95% CI：1.16 - 1.64）。在60岁以下人群中，睡眠时间超过9小时与高血压风险呈负相关（OR = 0.63，95% CI：0.47 - 0.86）。
睡眠时间少于5小时与高血压呈正相关。睡眠时间似乎可能影响高血压和动脉粥样硬化性心血管疾病。
