Khani Mehdi, Najafian Jamshid, Taheri Marzieh, Akhavan-Tabib Afshan, Hosseini Shidokht
MD Researcher, Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Associate Professor, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
ARYA Atheroscler. 2018 May;14(3):115-121. doi: 10.22122/arya.v14i3.1656.
Recent studies examining the association between sleep duration and cardiovascular disease (CVD) showed inconsistent results. The aim of our study was to evaluate the association between self-reported night sleep duration and ischemic changes in electrocardiography (ECG).
We conducted this cross-sectional study on 3513 participants from Iranian middle-aged population as a part of Isfahan Healthy Heart Program (IHHP), Isfahan, Iran. Sleep duration was obtained by questioning participants. The frequency of electrocardiographic ischemic changes was calculated using ECG Minnesota coding system.
Short sleep duration was associated with increased frequency of electrocardiographic ischemic changes. In a fully adjusted multiple logistic regression analysis, the odds ratio (OR) for short sleep duration less than 5 hours per night was 1.501 [95% confidence interval (CI) for OR: 1.085-2.076] compared to 8 hours of sleep. After stratifying the study population into sex groups, the association remained significant only in women. The OR for short sleep less than 5 hours per night was 1.565 (95% CI for OR: 1.052-2.329) and 1.455 (95% CI for OR: 0.833-2.539) in women and men, respectively. There was no association between long sleep duration and electrocardiographic ischemic changes in men and women.
We concluded that there is a positive association between short sleep duration and frequency of electrocardiographic ischemic changes in middle-aged women. This association suggests that short sleep duration may increase the risk of ischemic heart disease (IHD) in women, and this need to be evaluated in further studies.
近期关于睡眠时间与心血管疾病（CVD）关联的研究结果并不一致。我们研究的目的是评估自我报告的夜间睡眠时间与心电图（ECG）缺血性改变之间的关联。
作为伊朗伊斯法罕健康心脏项目（IHHP）的一部分，我们对来自伊朗中年人群的3513名参与者进行了这项横断面研究。通过询问参与者获得睡眠时间。使用心电图明尼苏达编码系统计算心电图缺血性改变的频率。
睡眠时间短与心电图缺血性改变频率增加有关。在完全调整的多因素逻辑回归分析中，与每晚8小时睡眠相比，每晚睡眠时间少于5小时的短睡眠时间的优势比（OR）为1.501 [OR的95%置信区间（CI）：1.085 - 2.076]。将研究人群按性别分组后，这种关联仅在女性中仍然显著。女性和男性每晚睡眠时间少于5小时的OR分别为1.565（OR的95% CI：1.052 - 2.329）和1.455（OR的95% CI：0.833 - 2.539）。男性和女性的长睡眠时间与心电图缺血性改变之间没有关联。
我们得出结论，中年女性的短睡眠时间与心电图缺血性改变频率之间存在正相关。这种关联表明短睡眠时间可能增加女性患缺血性心脏病（IHD）的风险，这需要在进一步研究中进行评估。
