Center of Clinical Pharmacology, The Third Xiangya Hospital, Central South University, Changsha, 410013, China.
National-Local Joint Engineering Laboratory of Drug Clinical Evaluation Technology, Changsha, 410000, China.
J Hum Hypertens. 2021 Oct;35(10):896-902. doi: 10.1038/s41371-020-00419-x. Epub 2020 Sep 24.
We aimed to investigate the association of self-reported nighttime sleep duration and daytime napping duration with hypertension in rural areas of China. The participants, who were from rural areas of Hunan Province in China, were enrolled during 2016-2017. Nighttime sleep duration (<7 h, 7-8 h, and ≥9 h) and daytime napping duration(no nap, 0-1 h, and >1 h) were determined by a self-reported questionnaire. Hypertension was defined as a mean systolic blood pressure ≥140 mmHg and/or a mean diastolic blood pressure ≥90 mmHg or a self-reported physician diagnosis of hypertension and current use of antihypertensive medication. Of 1763 enrolled participants, 52% had hypertension. A total of 640 (36%) were male and 1123 (64%) were female; the mean age was 56 years. After adjusting for potential confounders, participants who slept for ≥9 h per night had a 1.29-fold (95% CI: 1.03, 1.60) increased odds of hypertension compared to the reference group (7-8 h per night). Daytime napping >1 h was negatively associated with hypertension, with an adjusted OR (95% CI) of 0.70 (0.51, 0.97), and the protective effect of longer daytime napping was still found in the subgroup sleeping 7-8 h per night. Among the rural population in China, long nighttime sleep duration is associated with a higher prevalence of hypertension, and longer daytime napping is related to a decreased prevalence of hypertension.
我们旨在研究中国农村地区自述夜间睡眠时间和白天小睡时间与高血压的关联。参与者来自中国湖南省的农村地区，于 2016-2017 年期间入组。通过自报问卷确定夜间睡眠时间（<7 小时、7-8 小时和≥9 小时）和白天小睡时间（无小睡、0-1 小时和>1 小时）。高血压定义为平均收缩压≥140mmHg 和/或平均舒张压≥90mmHg 或自述医生诊断为高血压且目前正在使用降压药物。在 1763 名入组参与者中，有 52%患有高血压。共有 640 名（36%）为男性，1123 名（64%）为女性；平均年龄为 56 岁。在调整了潜在混杂因素后，每晚睡眠时间≥9 小时的参与者发生高血压的几率是参考组（每晚 7-8 小时）的 1.29 倍（95%CI：1.03，1.60）。白天小睡>1 小时与高血压呈负相关，调整后的 OR（95%CI）为 0.70（0.51，0.97），并且在每晚睡眠时间为 7-8 小时的亚组中仍然存在更长白天小睡的保护作用。在中国农村人口中，长夜间睡眠时间与高血压患病率升高有关，而较长的白天小睡时间与高血压患病率降低有关。
