Department of Kinesiology and Nutrition Sciences, School of Integrated Health Sciences, 4505 S Maryland Parkway, University of Nevada Las Vegas, Las Vegas, NV 89154, USA.
Nutrients. 2019 Aug 22;11(9):1983. doi: 10.3390/nu11091983.
Blood lipids are an important biomarker of cardiovascular health and disease. Among the lipid biomarkers that have been widely used to monitor and predict cardiovascular diseases (CVD), elevated LDL and low HDL cholesterol (C), as well as elevated triglyceride-rich lipoproteins, deserve special attention in their predictive abilities, and thus have been the targets of several therapeutic and dietary approaches to improving lipid profiles. Among natural foods and nutraceuticals, dietary berries are a rich source of nutrients, fiber, and various types of phytochemicals. Berries as whole fruits, juices, and purified extracts have been shown to lower total and LDL-C, and increase HDL-C in clinical studies in participants with elevated blood lipids, type 2 diabetes or metabolic syndrome. This short review aimed to further discuss the mechanisms and magnitude of the lipid-lowering effects of dietary berries, with emphasis on reported clinical studies. Based on the emerging evidence, colorful berry fruits may thus be included in a healthy diet for the prevention and management of CVD.
血脂是心血管健康和疾病的一个重要生物标志物。在广泛用于监测和预测心血管疾病 (CVD) 的脂质生物标志物中，升高的 LDL 和低 HDL 胆固醇 (C) 以及升高的富含甘油三酯的脂蛋白在预测能力方面值得特别关注，因此已成为几种治疗和饮食方法改善血脂谱的目标。在天然食物和营养保健品中，膳食浆果是营养、纤维和各种类型植物化学物质的丰富来源。在临床研究中，浆果作为完整的水果、果汁和纯化提取物，已被证明可以降低高血脂、2 型糖尿病或代谢综合征患者的总胆固醇和 LDL-C，并增加 HDL-C。本综述旨在进一步讨论膳食浆果降低血脂的作用机制和程度，重点是报告的临床研究。基于新出现的证据，彩色浆果水果可能因此被纳入健康饮食中，以预防和管理 CVD。
