McSharry C, Banham S W, Boyd G
Clin Allergy. 1985 Sep;15(5):487-94. doi: 10.1111/j.1365-2222.1985.tb02299.x.
There was a reduced prevalence of symptoms of Extrinsic Allergic Alveolitis (EAA) among the cigarette smokers in a survey of 102 volunteer pigeon breeders. These smokers had a significantly lower antibody response against the inhaled antigens associated with the disease; only one of twenty-three smokers (4.3%), but thirty-nine of sixty-five non-smokers (55.4%) had elevated serum IgG antibody levels, despite similar degrees of avian exposure in each group. The appearance of antibody in six of fourteen ex-smokers (42.9%) suggested that the apparent inhibitory effect of smoking on the antibody response was reversible. The smoking group had lower total serum IgG and IgA, higher serum IgD, and their total IgM and IgE levels were similar to the nonsmokers.
在一项针对102名志愿信鸽饲养者的调查中，吸烟者中外源性过敏性肺泡炎（EAA）症状的患病率较低。这些吸烟者针对与该疾病相关的吸入性抗原的抗体反应显著较低；在23名吸烟者中只有1人（4.3%）血清IgG抗体水平升高，但在65名不吸烟者中有39人（55.4%）血清IgG抗体水平升高，尽管每组的禽类接触程度相似。14名戒烟者中有6人（42.9%）出现抗体，这表明吸烟对抗体反应的明显抑制作用是可逆的。吸烟组的血清总IgG和IgA较低，血清IgD较高，其总IgM和IgE水平与不吸烟者相似。
