Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, China.
Department of Respiratory Diseases, The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou, China.
BMJ Open. 2019 Aug 22;9(8):e025891. doi: 10.1136/bmjopen-2018-025891.
Pneumoconiosis is characterised by diffuse fibrosis in lung tissue, and its incidence is on the rise. At present, there are limited therapeutic options for pneumoconiosis. Pulmonary rehabilitation (PR) has been widely used to treat pneumoconiosis，however, there is limited evidence concerning its efficacy. Therefore, we plan to conduct a systematic review to investigate the efficacy and safety of PR for pneumoconiosis.
The following databases will be searched from their inception to 1 April 2019: PubMed, Embase, The Cochrane Library, Web of Science, Chinese Biomedical Literature Database, China National Knowledge Infrastructure, Chongqing VIP and Wanfang Data. Randomised controlled trials of PR for pneumoconiosis will be included. Primary outcomes will include 6 min walk distance and St. George's Respiratory Questionnaire. Study selection, extraction of data and assessment of study quality each will be independently undertaken. Statistical analysis will be conducted using Review Manager software.
This systematic review will provide up-to-date information on PR for pneumoconiosis. The review does not require ethical approval and will be disseminated electronically through a peer-reviewed publication or conference presentations.
CRD42018095266.
尘肺的特征是肺部组织弥漫性纤维化，其发病率呈上升趋势。目前，尘肺的治疗选择有限。肺康复（PR）已广泛用于治疗尘肺，但关于其疗效的证据有限。因此，我们计划进行系统评价，以调查 PR 治疗尘肺的疗效和安全性。
将从各数据库建立起至 2019 年 4 月 1 日对以下数据库进行检索：PubMed、Embase、The Cochrane Library、Web of Science、中国生物医学文献数据库、中国知网、重庆维普和万方数据。将纳入 PR 治疗尘肺的随机对照试验。主要结局将包括 6 分钟步行距离和圣乔治呼吸问卷。将独立进行研究选择、数据提取和研究质量评估。统计分析将使用 Review Manager 软件进行。
本系统评价将提供最新的 PR 治疗尘肺信息。该综述不需要伦理批准，并将通过同行评审出版物或会议演示以电子方式传播。
PROSPERO 注册号：CRD42018095266。
