Dental and Periodontal Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Kidney Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Phytother Res. 2019 Nov;33(11):2927-2937. doi: 10.1002/ptr.6482. Epub 2019 Aug 26.
Curcumin is a dietary polyphenol and a bioactive phytochemical agent that possesses anti-inflammatory, antioxidant, anticancer, and chemopreventive properties. Some of the predominant activities of stem cells include regeneration of identical cells and the ability to maintain the proliferation and multipotentiality. However, these cells could be stimulated to differentiate into specific cell types. Curcumin protects some stem cells from toxicity and can stimulate proliferation and differentiation of stem cells. In the present review, we summarize the antioxidant, stemness activity, antiaging, and neuroprotective as well as wound healing and regenerative effects of curcumin.
姜黄素是一种膳食多酚和生物活性植物化学物质,具有抗炎、抗氧化、抗癌和化学预防特性。干细胞的一些主要活性包括相同细胞的再生和维持增殖及多能性的能力。然而,这些细胞可以被刺激分化为特定的细胞类型。姜黄素可以保护一些干细胞免受毒性的侵害,并可以刺激干细胞的增殖和分化。在本综述中,我们总结了姜黄素的抗氧化、干细胞活性、抗衰老、神经保护以及伤口愈合和再生作用。