Sajjadi Firoozeh, Mohammadifard Noushin, Maghroun Maryam, Shirani Fatemeh, Karimi Simin, Taheri Marzie, Sarrafzadegan Nizal
Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
Assistant Professor, Hypertension Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran.
ARYA Atheroscler. 2019 May;15(3):123-129. doi: 10.22122/arya.v15i3.1588.
Lifestyle modification is the most important strategy for control of obesity and overweight. Obestatin and adiponectin are the biomarkers of obesity. Thus, this study was performed to examine the effect of educational and encouragement interventions and lifestyle modifications on obesity anthropometric as well as obestatin and adiponectin levels.
This semi-experimental study was conducted on a subsample of TABASSOM study. Participants were 41 overweight and obese children and adolescents aged 6-18 years old and 45 overweight and obese adults aged 19-65 years old. Anthropometric characteristics including height, weight, waist and hip circumferences, and body fat percentage (BFP) were measured at the first and after one year at the end of study. We implemented some educational and encouragement interventions regarding dietary modification and physical activity during the study. Obestatin and adiponectin levels were measured at the first and end of study by enzyme-linked immunosorbent assay (ELISA) method.
The study did not show significant effect on anthropometric characteristics such as body mass index (BMI) and waist circumference (WC). BFP decreased significantly in boys, total children and adolescent group, and waist-to-hip ratio (WHR) decreased significantly only in adolescent boys after 1 year (P < 0.050).
Educational and encouraging interventions and lifestyle modifications could lead to decrease of body WHR and BFP in adolescent boys. This is helpful in controlling the increasing rate of obesity.
生活方式改变是控制肥胖和超重的最重要策略。肥胖抑制素和脂联素是肥胖的生物标志物。因此，本研究旨在探讨教育和鼓励干预以及生活方式改变对肥胖人体测量指标以及肥胖抑制素和脂联素水平的影响。
本半实验性研究是在TABASSOM研究的一个子样本上进行的。参与者为41名6至18岁的超重和肥胖儿童及青少年以及45名19至65岁的超重和肥胖成年人。在研究开始时和研究结束一年后测量身高、体重、腰围和臀围以及体脂百分比（BFP）等人体测量特征。在研究期间，我们实施了一些关于饮食调整和体育活动的教育和鼓励干预措施。通过酶联免疫吸附测定（ELISA）法在研究开始时和结束时测量肥胖抑制素和脂联素水平。
该研究未显示对体重指数（BMI）和腰围（WC）等人体测量特征有显著影响。一年后，男孩、儿童和青少年总体组的BFP显著下降，仅青少年男孩的腰臀比（WHR）显著下降（P<0.050）。
教育和鼓励干预以及生活方式改变可导致青少年男孩的身体WHR和BFP下降。这有助于控制肥胖率的上升。
