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尼日利亚一所医学院学生对抗生素使用和耐药性的了解情况。

Knowledge of antibiotic use and resistance among students of a medical school in Nigeria.

作者信息

Okedo-Alex Ijeoma, Madubueze Ugochukwu C, Umeokonkwo Chukwuma D, Oka Onyinyechukwu U, Adeke Azuka S, Okeke Kingsley C

机构信息

Department of Community Medicine, Federal Teaching Hospital Abakaliki Ebonyi State Nigeria.

Nigeria Field Epidemiology and Laboratory Training Programme Asokoro Abuja Nigeria.

出版信息

Malawi Med J. 2019 Jun;31(2):133-137. doi: 10.4314/mmj.v31i2.5.

DOI:10.4314/mmj.v31i2.5
PMID:31452846
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6698627/
Abstract

BACKGROUND

Antimicrobial resistance presents a growing concern worldwide. Medical students are potential antimicrobial prescribers and stewards following graduation as doctors. The aim of this study was to assess the knowledge regarding antibiotic use and resistance among pre-final year and final year medical school students of Ebonyi State University, Nigeria.

METHODS

A cross-sectional study was conducted among all the 184 pre-final and final year medical students of the College of Medicine at Ebonyi State University, Nigeria. Information was collected in April 2018 using a semi-structured, self-administered questionnaire and data were analysed with Epi-Info Version 7.2. Analytical decisions were considered significant at P < 0.05.

RESULTS

Respondents were mostly males (62.5%), aged 20-29 years (68.9%) with 60.9% of them in the final year class. Eighty-seven percent of them desired more education on antibiotic use and resistance. Majority 119 (64.7%) respondents had good knowledge of antibiotic use and resistance, however, 39% incorrectly answered that bacteria cause common cold. Only 103 (56.0%) of them had positive practice of antibiotic use. While 8.2% of respondents always consulted a doctor before starting an antibiotic. 37.2% of them never discarded their remaining leftover medications. Knowledge was associated with respondent's gender (P=0.035) while practice was associated with the class of study (P<0.001).

CONCLUSION

There was good knowledge of antibiotic use and resistance, however, practice levels were poor. There is need to enrich existing courses and training about antibiotic use in the curriculum of the medical schools with more emphasis on antimicrobial stewardship.

摘要

背景

抗菌药物耐药性在全球范围内日益受到关注。医学生毕业后有可能成为抗菌药物的开处方者和管理者。本研究的目的是评估尼日利亚埃邦伊州立大学医学预科最后一年和最后一年的医学生对抗生素使用和耐药性的了解情况。

方法

对尼日利亚埃邦伊州立大学医学院所有184名医学预科最后一年和最后一年的医学生进行了一项横断面研究。2018年4月使用半结构化的自填问卷收集信息,并使用Epi-Info 7.2版本进行数据分析。分析结果在P<0.05时被认为具有统计学意义。

结果

受访者大多为男性(62.5%),年龄在20-29岁之间(68.9%),其中60.9%为最后一年的学生。87%的人希望接受更多关于抗生素使用和耐药性的教育。大多数119名(64.7%)受访者对抗生素使用和耐药性有较好的了解,然而,39%的人错误地回答细菌会导致普通感冒。他们中只有103名(56.0%)有正确使用抗生素的习惯。8.2%的受访者在开始使用抗生素前总是咨询医生。37.2%的人从未丢弃剩余的药物。知识与受访者的性别有关(P=0.035),而习惯与学习班级有关(P<0.001)。

结论

对抗生素使用和耐药性有较好的了解,但实践水平较差。需要在医学院课程中丰富现有的关于抗生素使用的课程和培训,更加注重抗菌药物管理。

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