Azzam Martin J, Beutler Bryce D, Calame Antoanella, Erickson Christof P, Cohen Philip R
Internal Medicine, University of Nevada, Reno School of Medicine, Reno, USA.
Dermatology, Compass Dermatopathology, Inc., San Diego, USA.
Cureus. 2019 Jun 20;11(6):e4959. doi: 10.7759/cureus.4959.
Osteoma cutis is a benign cutaneous lesion characterized by the presence of bone within the dermis or subcutaneous fat. It most often develops in association with other skin lesions such as cutaneous tumors. Nevus sebaceus is a benign hamartoma of the skin that is composed of epidermal and dermal components. It most commonly appears on the scalp and may give rise to either benign or malignant secondary neoplasms. The clinical and pathologic features of a 36-year-old man with a nevus sebaceus and associated osteoma cutis are described. In addition, osteoma cutis-associated neoplasms are reviewed. Secondary osteoma cutis has been observed with both benign and malignant neoplasms as well as various non-neoplastic skin conditions. However, to the best of our knowledge, osteoma cutis has not previously been described in association with nevus sebaceus. Nevus sebaceus can now be added to the list of cutaneous osteoma-associated skin tumors (COASTs).
皮肤骨瘤是一种良性皮肤病变,其特征是真皮或皮下脂肪内存在骨组织。它最常与其他皮肤病变如皮肤肿瘤相关联而发生。皮脂腺痣是一种由表皮和真皮成分组成的皮肤良性错构瘤。它最常见于头皮,可能会引发良性或恶性继发性肿瘤。本文描述了一名36岁患有皮脂腺痣及相关皮肤骨瘤男性的临床和病理特征。此外,还对与皮肤骨瘤相关的肿瘤进行了综述。继发性皮肤骨瘤已在良性和恶性肿瘤以及各种非肿瘤性皮肤疾病中观察到。然而,据我们所知,此前尚未有皮肤骨瘤与皮脂腺痣相关的描述。皮脂腺痣现在可被添加到与皮肤骨瘤相关的皮肤肿瘤(COASTs)列表中。