Borman Pınar, Yaman Ayşegül, Denizli Merve, Karahan Sevilay, Özdemir Oya
Department of Physical Medicine and Rehabilitation, Medicine Faculty of Hacettepe University, Ankara, Turkey.
University of Hacettepe Lymphedema Practice and Research Center, Ankara, Turkey.
Turk J Phys Med Rehabil. 2018 Jul 9;64(3):205-212. doi: 10.5606/tftrd.2018.2843. eCollection 2018 Sep.
This study aims to adapt Lymphedema Quality of Life Questionnaire-Arm (LYMQOL) into Turkish and to test its reliability and validity in Turkish patients with upper limb lymphedema related with breast cancer.
Between June 2015 and November 2015, the Turkish LYMQOL-Arm was obtained using forward-backward translation method and administered to a total of 135 female patients (mean age 51.8±9.8 years; range, 31 to 82 years) with upper limb lymphedema with European Organization for Research and Treatment of Cancer-QoL Breast Cancer-specific version (EORTC QLQ-BR23) and Functional Assessment of Cancer Therapy-Breast-4 (FACT-B+4) questionnaires. A test-retest interval of seven-days was used to assess the reliability. The validation studies were carried-out by means of construct-validity using Spearman's rank correlation-coefficient. Internal consistency and test-retest-reliability were assessed using Cronbach's alpha and intra-class correlation-coefficient (ICC), respectively.
135 patients completed the questionnaire with upper limb lymphedema related with breast cancer completed the questionnaires. The mean lymphedema duration was 21.1±28.7 (median: 6) months. Internal consistency and reliability of the Turkish LYMQOL-Arm was good with Cronbach's alpha (0.88-0.90) and test-retest ICC (0.45-0.71). External construct validity was highly confirmed by expected correlations with comparator scales, EORTCQLQ-BR23 and FACT-B+4 (p<0.01).
The Turkish version of the LYMQOL-Arm is a valid and reliable tool for evaluating QoL in female patients with upper limb lymphedema related with breast cancer.
本研究旨在将上肢淋巴水肿生活质量问卷（LYMQOL）改编为土耳其语版本，并在土耳其乳腺癌相关上肢淋巴水肿患者中测试其信效度。
2015年6月至2015年11月期间，采用正反翻译法获取土耳其语版LYMQOL上肢问卷，并将其应用于135例女性患者（平均年龄51.8±9.8岁；范围31至82岁），这些患者患有上肢淋巴水肿，同时还使用了欧洲癌症研究与治疗组织乳腺癌特异性生活质量问卷（EORTC QLQ-BR23）和癌症治疗功能评价量表-乳腺癌4（FACT-B+4）问卷。采用7天的重测间隔来评估信度。通过使用Spearman等级相关系数进行结构效度分析来开展效度研究。分别使用Cronbach's α系数和组内相关系数（ICC）评估内部一致性和重测信度。
135例患有乳腺癌相关上肢淋巴水肿的患者完成了问卷。淋巴水肿的平均持续时间为21.1±28.7（中位数：6）个月。土耳其语版LYMQOL上肢问卷的内部一致性和信度良好，Cronbach's α系数为0.88 - 0.90，重测ICC为0.45 - 0.71。与对照量表EORTC QLQ-BR23和FACT-B+4的预期相关性高度证实了外部结构效度（p<0.01）。
土耳其语版LYMQOL上肢问卷是评估乳腺癌相关上肢淋巴水肿女性患者生活质量的有效且可靠的工具。
