Li Shengwen Calvin, Luo Jane, Lee Katherine L
Department of Neurology, University of California-Irvine (UCI) School of Medicine; Children's Hospital of Orange County (CHOC), CHOC Children's Research Institute, Neuro-Oncology and Stem Cell Research Laboratory (NSCL), USA.
AB Sciex, Inc., Danaher Corporation, USA.
Online J Complement Altern Med. 2019;1(3). doi: 10.33552/OJCAM.2019.01.000514. Epub 2019 Jun 11.
Cancer epidemic led to worldwide to search for a new "game changer" concept to govern cancer research and cancer treatment. Western medicine-based cancer research has been extending the impasse without resolution in sigh for improving survival of patients with solid malignant tumors in the last four decades due to heterogeneity in cancer tissues. Such a deadlock charts a course to learn lessons from the developing countries, directly or indirectly to complement the exhausted Western medicine. We propose a new concept of "Cancer niche as a garbage disposal machine" with implications of traditional Chinese medicine-mediated restoration of normal balance between body and disease to bring the fight against cancer under control.
癌症流行促使全球寻找新的“变革性”概念来指导癌症研究和治疗。在过去的四十年里,基于西医的癌症研究一直陷入僵局,由于癌症组织的异质性,在改善实体恶性肿瘤患者生存率方面毫无进展。这种僵局促使人们直接或间接地从发展中国家吸取经验教训,以补充已穷尽的西医方法。我们提出了一个新的概念“癌症生态位作为垃圾处理机”,其蕴含着中医介导的恢复身体与疾病之间正常平衡,从而控制抗癌斗争的意义。