Connor Daniel F, Newcorn Jeffrey H, Saylor Keith E, Amann Birgit H, Scahill Lawrence, Robb Adelaide S, Jensen Peter S, Vitiello Benedetto, Findling Robert L, Buitelaar Jan K
Department of Psychiatry, Division of Child & Adolescent Psychiatry, University of Connecticut Medical School, Farmington, Connecticut.
Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, New York.
J Child Adolesc Psychopharmacol. 2019 Oct;29(8):576-591. doi: 10.1089/cap.2019.0039. Epub 2019 Aug 27.
Aggressive behavior is among the most common reasons for referral to psychiatric clinics and confers significant burden on individuals. Aggression remains poorly defined; there is currently no consensus on the best ways to recognize, diagnose, and treat aggression in clinical settings. In this review, we synthesize the available literature on aggression in children and adolescents and propose the concept of impulsive aggression (IA) as an important construct associated with diverse and enduring psychopathology. Articles were identified and screened from online repositories, including PubMed, PsychInfo, the Cochrane Database, EMBase, and relevant book chapters, using combinations of search terms such as "aggression," "aggressive behavio(u)r," "maladaptive aggression," "juvenile," and "developmental trajectory." These were evaluated for quality of research before being incorporated into the article. The final report references 142 sources, published from 1987 to 2019. Aggression can be either adaptive or maladaptive in nature, and the latter may require psychosocial and biomedical interventions when it occurs in the context of central nervous system psychopathology. Aggression can be categorized into various subtypes, including reactive/proactive, overt/covert, relational, and IA. IA in psychiatric or neurological disorders is reviewed along with current treatments, and an algorithm for systematic evaluation of aggression in the clinical setting is proposed. IA is a treatable form of maladaptive aggression that is distinct from other aggression subtypes. It occurs across diverse psychiatric and neurological diagnoses and affects a substantial subpopulation. IA can serve as an important construct in clinical practice and has considerable potential to advance research.
攻击性行为是转介到精神科诊所的最常见原因之一,给个人带来了沉重负担。攻击性行为的定义仍不明确;目前对于在临床环境中识别、诊断和治疗攻击性行为的最佳方法尚无共识。在本综述中,我们综合了关于儿童和青少年攻击性行为的现有文献,并提出冲动性攻击(IA)这一概念,作为与多种持久精神病理学相关的重要结构。通过使用“攻击”“攻击行为”“适应不良的攻击”“青少年”和“发育轨迹”等搜索词组合,从包括PubMed、PsychInfo、Cochrane数据库、EMBase以及相关书籍章节在内的在线数据库中识别和筛选文章。在将这些文章纳入本文之前,对其研究质量进行了评估。最终报告引用了1987年至2019年发表的142篇文献。攻击性行为本质上既可以是适应性的,也可以是适应不良的,当后者发生在中枢神经系统精神病理学背景下时,可能需要心理社会和生物医学干预。攻击性行为可分为多种亚型,包括反应性/主动性、公开/隐蔽性、关系性和IA。本文回顾了精神科或神经科疾病中的IA以及当前的治疗方法,并提出了一种在临床环境中系统评估攻击性行为的算法。IA是一种可治疗的适应不良攻击形式,与其他攻击亚型不同。它出现在各种精神科和神经科诊断中,并影响相当一部分人群。IA可作为临床实践中的重要结构,具有推动研究的巨大潜力。