Weight Control and Diabetes Research Center, The Miriam Hospital, Providence, RI, USA.
Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Providence, RI, USA.
AIDS Behav. 2020 Apr;24(4):1085-1091. doi: 10.1007/s10461-019-02645-y.
Obesity and chronic disease are growing problems among people living with HIV (PLWH) across the globe. While a variety of treatments have been developed to address cardiovascular and metabolic disease among PLWH, few treatments have focused on helping PLWH and obesity lose weight. In the general population, behavioral weight loss interventions (i.e., diet, physical activity, and behavior therapy) are the first-line treatment for adults for whom weight loss is recommended. However, little research has tested whether the benefits of these programs translate to PLWH. This paper highlights the key components of behavioral weight loss programs, their outcomes in the general population and in the few studies of PLWH, and suggestions for tailoring these programs for PLWH. Behavioral weight loss programs are a strong potential treatment for reducing the burden of obesity among PLWH and merit future research attention.
肥胖和慢性病是全球 HIV 感染者（PLWH）中日益严重的问题。虽然已经开发出各种治疗方法来解决 PLWH 中的心血管和代谢疾病，但很少有治疗方法专注于帮助 PLWH 和肥胖者减肥。在普通人群中，行为减肥干预措施（即饮食、体育活动和行为疗法）是推荐减肥的成年人的一线治疗方法。然而，很少有研究测试这些方案的好处是否适用于 PLWH。本文重点介绍行为减肥方案的关键组成部分、它们在普通人群中的结果以及在少数 PLWH 研究中的结果，以及为 PLWH 量身定制这些方案的建议。行为减肥方案是降低 PLWH 肥胖负担的强有力潜在治疗方法，值得未来的研究关注。
