Kamitani Emiko, Sipe Theresa Ann, Higa Darrel H, Mullins Mary M, Soares Jesus
ORISE Fellow, Prevention Research Branch, Division of HIV/AIDS Prevention, U.S. Centers for Disease Control and Prevention, Atlanta, Georgia.
Prevention Research Branch, Division of HIV/AIDS Prevention, U.S. Centers for Disease Control and Prevention.
AIDS Educ Prev. 2017 Aug;29(4):347-363. doi: 10.1521/aeap.2017.29.4.347.
Physical exercise (PE) has not been well studied in persons living with HIV (PLHIV). We conducted an overview of systematic reviews to assess the effectiveness of PE and to determine the most appropriate PE regimen for PLHIV. We used the CDC's Prevention Research Synthesis Project's database and manual searches to identify systematic reviews published between 1996 and 2013. We qualitatively synthesized the findings from five reviews to assess the effectiveness of PE and conducted meta-analyses on CD4 counts to identify the best PE regimen. PE is associated with reduced adiposity and depression, but was not associated with a decrease in HIV viral load. CD4 counts were improved by interventions with interval aerobic or 41-50 minutes of exercise three times per week compared with other modes and duration of exercise. PE appears to benefit PLHIV, but more research is needed to help develop appropriate PE strategies specifically for PLHIV.
体育锻炼（PE）在艾滋病毒感染者（PLHIV）中的研究尚不充分。我们进行了一项系统评价综述，以评估体育锻炼的有效性，并确定最适合艾滋病毒感染者的体育锻炼方案。我们使用美国疾病控制与预防中心（CDC）预防研究综合项目的数据库并进行人工检索，以识别1996年至2013年间发表的系统评价。我们对五项综述的结果进行了定性综合分析，以评估体育锻炼的有效性，并对CD4细胞计数进行荟萃分析，以确定最佳的体育锻炼方案。体育锻炼与肥胖和抑郁的减轻有关，但与艾滋病毒病毒载量的降低无关。与其他运动方式和时长相比，每周进行三次间歇有氧运动或41 - 50分钟运动的干预措施可提高CD4细胞计数。体育锻炼似乎对艾滋病毒感染者有益，但需要更多研究来帮助制定专门针对艾滋病毒感染者的适当体育锻炼策略。
