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绿色纳米技术驱动的药物递送组件

Green Nanotechnology-Driven Drug Delivery Assemblies.

作者信息

Kanwar Rohini, Rathee Jyoti, Salunke Deepak B, Mehta Surinder K

机构信息

Department of Chemistry and Center of Advanced Studies in Chemistry, Panjab University, Chandigarh U.T. 160014, India.

出版信息

ACS Omega. 2019 May 22;4(5):8804-8815. doi: 10.1021/acsomega.9b00304. eCollection 2019 May 31.

DOI:10.1021/acsomega.9b00304
PMID:31459969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6648705/
Abstract

Green nanotechnology incorporates the principles of green chemistry and green engineering to fabricate innocuous and eco-friendly nanoassemblies to combat the problems affecting the human health or environment. Subsequently, amalgamation of green nanotechnology with drug delivery area has actually commenced a new realm of "green nanomedicine". The burgeoning demand for green nanotechnology-driven drug delivery systems has led to the development of different types of delivery devices, like inorganic (metallic) nanoparticles, quantum dots, organic polymeric nanoparticles, mesoporous silica nanoparticles, dendrimers, nanostructured lipid carriers, solid lipid nanoparticles, etc. The present article deals with a brief account of delivery devices produced from green methods and describes site-specific drug delivery systems (including their pros and cons) and their relevance in the field of green nanomedicine.

摘要

绿色纳米技术融合了绿色化学和绿色工程的原理,以制造无害且环保的纳米组件,以应对影响人类健康或环境的问题。随后,绿色纳米技术与药物递送领域的融合实际上开启了一个“绿色纳米医学”的新领域。对绿色纳米技术驱动的药物递送系统的迅速增长的需求导致了不同类型递送装置的发展,如无机(金属)纳米颗粒、量子点、有机聚合物纳米颗粒、介孔二氧化硅纳米颗粒、树枝状大分子、纳米结构脂质载体、固体脂质纳米颗粒等。本文简要介绍了通过绿色方法生产的递送装置,并描述了位点特异性药物递送系统(包括其优缺点)及其在绿色纳米医学领域的相关性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a406/6648705/022a43ce9d47/ao-2019-003047_0006.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a406/6648705/3a37c002ad0a/ao-2019-003047_0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a406/6648705/53b3eb79a18f/ao-2019-003047_0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a406/6648705/4d009e8de20a/ao-2019-003047_0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a406/6648705/ca2187418f88/ao-2019-003047_0004.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a406/6648705/022a43ce9d47/ao-2019-003047_0006.jpg

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