零价铁和碳负载铂在2-丙醇中催化芳烃的Birch型还原反应

Sawama Yoshinari, Ban Kazuho, Akutsu-Suyama Kazuhiro, Nakata Hiroki, Mori Misato, Yamada Tsuyoshi, Kawajiri Takahiro, Yasukawa Naoki, Park Kwihwan, Monguchi Yasunari, Takagi Yukio, Yoshimura Masatoshi, Sajiki Hironao

Laboratory of Organic Chemistry, Gifu Pharmaceutical University, 1-25-4, Daigaku-nishi, Gifu 501-1196, Japan.

Neutron Science and Technology Center, Comprehensive Research Organization for Science and Society (CROSS), 162-1 Shirakata, Tokai-Mura, Naka-gun, Ibaraki 319-1106, Japan.

ACS Omega. 2019 Jul 2;4(7):11522-11531. doi: 10.1021/acsomega.9b01130. eCollection 2019 Jul 31.

Catalytic arene reduction was effectively realized by heating in 2-propanol/water in the presence of Pt on carbon (Pt/C) and metallic Fe. 2-Propanol acted as a hydrogen source, obviating the need for flammable (and hence, dangerous and hard-to-handle) hydrogen gas, while metallic Fe acted as an essential co-catalyst to promote reduction. The chemical states of Pt and Fe in the reaction mixture were determined by X-ray absorption near-edge structure analysis, and the obtained results were used to suggest a plausible reaction mechanism, implying that catalytic reduction involved Pt- and Fe-mediated single-electron transfer and the dehydrogenation of 2-propanol.

在炭载铂（Pt/C）和金属铁存在的情况下，通过在异丙醇/水中加热，有效地实现了催化芳烃还原反应。异丙醇作为氢源，无需使用易燃（因此危险且难以处理）的氢气，而金属铁作为促进还原反应的关键助催化剂。通过X射线吸收近边结构分析确定了反应混合物中Pt和Fe的化学状态，并利用所得结果提出了一个合理的反应机理，这表明催化还原涉及Pt和Fe介导的单电子转移以及异丙醇的脱氢反应。