定量血管内体积与高血压患者血压的相关性。
Correlation of Quantitated Intravascular Volume with Blood Pressure in Patients with Systemic Hypertension.
机构信息
Department of Medicine, Division of Cardiology, Duke University Medical Center, Durham, NC, USA.
Duke Clinical Research Institute, Durham, NC, USA.
出版信息
J Cardiovasc Transl Res. 2020 Aug;13(4):528-530. doi: 10.1007/s12265-019-09910-4. Epub 2019 Aug 28.
Volume management is an essential component of anti-hypertensive therapy. Different volume phenotypes have been proposed. We sought to study the total blood volume (TBV), plasma volume (PV), and red blood cell volume (RBV) in hypertensive patients. We included patients followed in an outpatient cardiology clinic from 1998 to 2003. Blood volume (BV) parameters were measured using radioisotope iodine-131-labeled albumin dilution technique. Values were expressed as percentage (%) deviation from ideal volumes. A total of 95 patients were included. The intravascular volume distribution as percent deviation from normal volume ranged from - 23 to + 28% for TBV, - 22 to + 36% for PV and - 29 to + 37% for RBV. There was no significant correlation between systolic BP and any of the BV parameters (TBV and SBP, r = - 0.03; PV and SBP, r = - 0.12; RBV and SBP, r = - 0.08). Patients with hypertension have a wide variation in BV parameters. BV does not correlate with SBP.
容量管理是抗高血压治疗的重要组成部分。已经提出了不同的容量表型。我们试图研究高血压患者的总血容量（TBV）、血浆容量（PV）和红细胞容量（RBV）。我们纳入了 1998 年至 2003 年在门诊心内科就诊的患者。使用放射性碘 131 标记白蛋白稀释技术测量血容量（BV）参数。结果表示为与理想体积的百分比偏差。共纳入 95 例患者。从正常体积的百分比偏差来看，TBV 的血管内容量分布范围为-23%至+28%，PV 为-22%至+36%，RBV 为-29%至+37%。收缩压与任何 BV 参数之间均无显著相关性（TBV 和 SBP，r=-0.03；PV 和 SBP，r=-0.12；RBV 和 SBP，r=-0.08）。高血压患者的 BV 参数变化范围较大。BV 与 SBP 不相关。
Zotero 插件