Opt Lett. 2019 Sep 1;44(17):4171-4174. doi: 10.1364/OL.44.004171.
In this work, we investigated the use of optoelectronic tweezers (OET) to manipulate objects that are larger than those commonly positioned with standard optical tweezers. We studied the forces that could be produced on differently sized polystyrene microbeads and MCF-7 breast cancer cells with light-induced dielectrophoresis (DEP). It was found that the DEP force imposed on the bead/cell did not increase linearly with the volume of the bead/cell, primarily because of the non-uniform distribution of the electric field above the OET bottom plate. Although this size-scaling work focuses on microparticles and cells, we propose that the physical mechanism elucidated in this research will be insightful for other micro-objects, biological samples, and micro-actuators undergoing OET manipulation.
在这项工作中，我们研究了使用光镊（OET）来操纵比通常使用标准光镊定位的物体更大的物体。我们研究了光诱导介电泳（DEP）对不同大小的聚苯乙烯微球和 MCF-7 乳腺癌细胞产生的力。结果发现，施加在微球/细胞上的 DEP 力不会随微球/细胞的体积线性增加，主要是因为 OET 底板上方电场的不均匀分布。虽然这项关于微球和细胞的尺寸缩放工作是重点，但我们提出，在这项研究中阐明的物理机制将为其他正在经历 OET 操作的微物体、生物样本和微执行器提供有见地的见解。
