Esteves Leandro João, Meira Jorge, Ferreira Carla Sofia, Santos-Silva Renato, Freitas-Costa Paulo, Magalhães Augusto, Breda Jorge, Falcão-Reis Fernando
Department of Ophthalmology, São João Hospital, Porto, Portugal.
Department of Surgery and Physiology, Faculty of Medicine, University of Porto, Porto, Portugal.
J Ophthalmol. 2019 Aug 5;2019:3267151. doi: 10.1155/2019/3267151. eCollection 2019.
To evaluate the efficacy of the "fogging test," performed with a +2 diopters (D) lens, in the exclusion of clinically significant hyperopia in school-aged children.
We studied 54 children between 5 and 11 years of age, with 10/10 best-corrected bilateral visual acuity (VA) without significant degree of correction. VA was assessed in each eye with a "bilateral" +2 D sphere over-refraction followed by cycloplegic retinoscopy. The capacity of the test to detect hyperopia of ≥+2 D and ≥+1.5 D was evaluated by examining the respective receiver operating characteristic (ROC) curves and sensitivity and specificity values for different cutoff values of VA.
For the detection of hyperopia ≥+2 D, the area under the ROC curve (AUC) was 0.955 ( ≤ 0.001). The VA cutoff with best discriminative capacity was ≥5/10, with a sensitivity of 100%, specificity of 79%, positive predictive value (PPV) of 57%, and negative predictive value (NPV) of 100%. In respect of ≥+1.5 D hyperopia, the test capacity was lower (AUC = 0.832; ≤ 0.001). The best VA cutoff was also of ≥5/10, with a PPV of 81% and a NPV of 85%.
The accuracy of the test was high for the evaluation of ≥+2 D hyperopia but lower for ≥+1.5 D hyperopia. For the detection of ≥+2 D hyperopia, the VA cutoff of <5/10 may permit the exclusion of clinically significant hyperopia in selected children, without the need for cycloplegia. For the same cutoff, the PPV was low, meaning that in children with ≥5/10 VA cycloplegic refraction remains obligatory.
评估使用 +2 屈光度(D)镜片进行的“雾化试验”在排除学龄儿童临床显著远视方面的效果。
我们研究了 54 名 5 至 11 岁的儿童,其双眼最佳矫正视力(VA)均为 10/10,且矫正度数无显著差异。每只眼睛均通过“双眼” +2 D 球镜过矫验光,随后进行睫状肌麻痹验光来评估 VA。通过检查不同 VA 临界值对应的各自的受试者工作特征(ROC)曲线以及敏感性和特异性值,评估该试验检测≥ +2 D 和≥ +1.5 D 远视的能力。
对于检测≥ +2 D 的远视,ROC 曲线下面积(AUC)为 0.955(≤ 0.001)。具有最佳判别能力的 VA 临界值为≥ 5/10,敏感性为 100%,特异性为 79%,阳性预测值(PPV)为 57%,阴性预测值(NPV)为 100%。对于≥ +1.5 D 的远视,该试验能力较低(AUC = 0.832;≤ 0.001)。最佳 VA 临界值同样为≥ 5/10,PPV 为 81%,NPV 为 85%。
该试验在评估≥ +2 D 远视时准确性较高,但在评估≥ +1.5 D 远视时准确性较低。对于检测≥ +2 D 的远视,VA 临界值 <5/10 可能允许在特定儿童中排除临床显著远视,而无需进行睫状肌麻痹。对于相同的临界值,PPV 较低,这意味着 VA≥ 5/1