Suppr超能文献

痔病的吻合器痔上黏膜环切钉合术联合 Proctonorm® 治疗

Integrated Treatment With Stapled Haemorrhoidopexy and Proctonorm® of Haemorrhoidal Disease.

机构信息

Department of Surgery, Coloproctology Unit - Casa di Cura San Camillo, Forte dei Marmi (Lucca), Italy.

Breast Surgery Clinic, Osp. Policlinico San Martino, Genoa, Italy

出版信息

In Vivo. 2019 Sep-Oct;33(5):1671-1675. doi: 10.21873/invivo.11654.

Abstract

BACKGROUND/AIM: This retrospective study was performed in patients undergoing Stapled Haemorrhoidopexy (SH) who were post-operatively treated with Proctonorm® with the aim of assessing its effect on early and late haemorrhoidal-related symptoms.

PATIENTS AND METHODS

Forty-six males and 54 females received Proctonorm® (one tablet twice daily for 14 days) and Ketoprofene R (200 mg, one tablet twice daily, as requested).

RESULTS

"Early Complication Score" (0-12) two days after surgery was 2.02±1.03; pain VAS (Visual Analogue Scale) (0-10) was 1.21±0.89, and the number of anti-inflammatory tablets was 4.24±1.06. At 40-day post-operative assessment, seven patients had post-operative complications with "Late Complication Score" (0-20) of 0.34±0.68. At six-month follow-up, a high index of patient satisfaction (VAS=9.39±0.24) was self-reported with 75% reduction in CSS (Constipation Scoring System) (1.95±2.58) compared to preoperative scores; "Late Complication Score" was 0.

CONCLUSION

The specific target activity of Proctonorm® at the microcircular level may be effective in patients undergoing SH in order to reduce the inflammatory response of residual haemorrhoids while waiting for stable resolution of symptoms within one or two weeks.

摘要

背景/目的:本回顾性研究针对接受吻合器痔上黏膜环切术(SH)的患者,术后使用 Proctonorm®进行治疗,旨在评估其对早期和晚期痔相关症状的影响。

患者与方法

46 名男性和 54 名女性患者接受 Proctonorm®(每天两次,每次一片,共 14 天)和酮咯酸(Ketoprofene R)(每天两次,每次一片,按需服用)治疗。

结果

术后两天的“早期并发症评分”(0-12)为 2.02±1.03;疼痛视觉模拟评分(VAS)(0-10)为 1.21±0.89,抗炎药片数为 4.24±1.06。术后 40 天评估时,7 名患者出现术后并发症,“晚期并发症评分”(0-20)为 0.34±0.68。6 个月随访时,患者自我报告的满意度指数(VAS=9.39±0.24)较高,与术前评分相比,CSS(便秘评分系统)(1.95±2.58)降低了 75%;“晚期并发症评分”为 0。

结论

Proctonorm®在微循环水平的特定靶向活性可能对接受 SH 的患者有效,以减少残留痔的炎症反应,同时等待症状在一到两周内稳定缓解。

相似文献

4
Surgical treatment of recurrent prolapse after stapled haemorrhoidopexy.
Tech Coloproctol. 2014 Sep;18(9):847-50. doi: 10.1007/s10151-014-1180-6. Epub 2014 Jun 24.

本文引用的文献

2
Properties and therapeutic application of bromelain: a review.菠萝蛋白酶的特性与治疗应用:综述
Biotechnol Res Int. 2012;2012:976203. doi: 10.1155/2012/976203. Epub 2012 Dec 10.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验