Galal S H, Khalil S H, el Husseiny W, Brock J
Faculty of Medicine, Alexandria University.
Allerg Immunol (Leipz). 1988;34(4):249-54.
The present study was devoted to assess the humoral and cell mediated immune responsiveness in patients with pulmonary tuberculosis before and after rifampicin therapy. Skin test using PPD and PHA; Rosette forming cells test, serum IgG, M and A; and light chain proteinuria have been tested for 15 newly diagnosed tuberculous patients and 15 normal controls. Rifampicin showed an immunosuppressive effect on both cellular and humoral immune responses as well as by the advent of light chain proteinuria.
本研究旨在评估利福平治疗前后肺结核患者的体液免疫和细胞介导免疫反应性。对15例新诊断的结核患者和15例正常对照者进行了使用结核菌素纯蛋白衍生物（PPD）和植物血凝素（PHA）的皮肤试验、玫瑰花结形成细胞试验、血清免疫球蛋白G（IgG）、M和A以及轻链蛋白尿检测。利福平对细胞免疫和体液免疫反应均显示出免疫抑制作用，同时还出现了轻链蛋白尿。
