Santos Silva João, Torres Carolina, Clemente Susana, Calvinho Paulo
Cardiothoracic Surgery Department, Hospital Beatriz Ângelo, Loures, Portugal.
General Surgery, Emergency Department, Hospital Beatriz Ângelo, Loures, Portugal.
Rev Port Cir Cardiotorac Vasc. 2019 Apr-Jun;26(2):151-153.
Mucormycosis is a life-threatening fungal infection that occurs mainly in immunocompromised patients. Its occurrence isolated in the lung rare and carries a high mortality risk if untreated. We report the case of a 76-year old male immunocompetent patient, under treatment for pulmonary tuberculosis, admitted to the emergency department with hemoptysis. Bronchoscopy was performed and active bleeding from the middle lobe bronchus was found. Chest CT scan identified a solitary cavitary lesion in the middle lobe. The patient was proposed for urgent open middle lobectomy. Postoperative period was uneventful. Pulmonary mucormycosis was confirmed and adjuvant therapy with Amphotericin B was performed for 30 days. Despite its rarity, mucormycosis prevalence is expected to raise together with increasing number of immunocompromised patients. A high level of suspicion is recommended as early diagnosis can be determinant.
毛霉菌病是一种危及生命的真菌感染，主要发生在免疫功能低下的患者中。其在肺部孤立发生的情况罕见，如果不治疗，死亡率很高。我们报告一例76岁免疫功能正常的男性患者，因肺结核正在接受治疗，因咯血入住急诊科。进行了支气管镜检查，发现中叶支气管有活动性出血。胸部CT扫描显示中叶有一个孤立的空洞性病变。该患者被建议进行紧急开放性中叶切除术。术后过程顺利。确诊为肺毛霉菌病，并使用两性霉素B进行了30天的辅助治疗。尽管毛霉菌病罕见，但随着免疫功能低下患者数量的增加，其患病率预计会上升。建议高度怀疑，因为早期诊断可能是决定性的。
