微波辅助从洋葱皮中提取酚类抗氧化剂的深共熔溶剂萃取：基于Box-Behnken设计法的优化研究
Microwave-assisted deep eutectic solvent extraction of phenolic antioxidants from onion ( L.) peel: a Box-Behnken design approach for optimization.
作者信息
Pal Chandra Bhushan T, Jadeja Girirajsinh C
机构信息
Chemical Engineering Department, S. V. National Institute of Technology, Surat, Gujarat 395007 India.
出版信息
J Food Sci Technol. 2019 Sep;56(9):4211-4223. doi: 10.1007/s13197-019-03891-7. Epub 2019 Jul 12.
Abstract
Valorization of onion peel waste, considered to be a rich source of polyphenolic compounds, by employing green extraction techniques is the need of the hour. The aim of the present study was to optimize the microwave-assisted extraction of bioactive phenolic compounds from onion peel wastes employing ChCl:Urea:HO deep eutectic solvent. Microwave power (100-200-300 W), time (5-15-25 min) and liquid to solid ratio (40:1-50:1-60:1) were studied as the major parameters affecting the extraction efficiency. A Box-Behnken design was adopted including 17 experiments with five centre points. The optimum conditions determined were 100 W microwave power, 15.03 min irradiation time and 54.97 mL g liquid to solid ratio. Under the MAE optimized conditions, the recovery of TPC and FRAP were 80.45 (mg GAE g dw) and 636.18 (µmol AAE g dw), respectively. Morphology of onion peels before and after DES extraction were also studied to gain an insight in the effect of microwave irradiations on the biomass.
摘要
采用绿色提取技术将被视为富含多酚类化合物的洋葱皮废料加以增值利用是当务之急。本研究的目的是优化利用氯化胆碱：尿素：水的深层共熔溶剂从洋葱皮废料中微波辅助提取生物活性酚类化合物的工艺。研究了微波功率（100 - 200 - 300瓦）、时间（5 - 15 - 25分钟）和液固比（40:1 - 50:1 - 60:1）作为影响提取效率的主要参数。采用Box - Behnken设计，包括17个实验和5个中心点。确定的最佳条件为100瓦微波功率、15.03分钟辐照时间和54.97毫升/克液固比。在微波辅助提取优化条件下，总酚含量（TPC）和铁还原抗氧化能力（FRAP）的回收率分别为80.45（毫克没食子酸当量/克干重）和636.18（微摩尔抗坏血酸当量/克干重）。还研究了深层共熔溶剂提取前后洋葱皮的形态，以深入了解微波辐照对生物质的影响。
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本文引用的文献
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2
Temperature-dependent studies on the total phenolics, flavonoids, antioxidant activities, and sugar content in six onion varieties.六个洋葱品种中总酚、黄酮类化合物、抗氧化活性及糖分含量的温度依赖性研究
J Food Drug Anal. 2015 Jun;23(2):243-252. doi: 10.1016/j.jfda.2014.10.005. Epub 2014 Dec 27.
3
Ultrasound-assisted extraction process of phenolic antioxidants from Olive leaves: a nutraceutical study using RSM and LC-ESI-DAD-MS.超声辅助从橄榄叶中提取酚类抗氧化剂的工艺：一项使用响应面法和液相色谱-电喷雾电离-二极管阵列-质谱联用技术的营养保健品研究
J Food Sci Technol. 2017 Jul;54(8):2361-2371. doi: 10.1007/s13197-017-2676-7. Epub 2017 Jun 19.
4
Economical and environmentally-friendly approaches for usage of onion (Allium cepa L.) waste.洋葱（葱属植物）废弃物利用的经济且环保方法。
Food Funct. 2016 Aug 10;7(8):3354-69. doi: 10.1039/c6fo00251j. Epub 2016 Jul 26.
5
Countercurrent assisted quantitative recovery of metabolites from plant-associated natural deep eutectic solvents.逆流辅助从植物相关天然低共熔溶剂中定量回收代谢物
Fitoterapia. 2016 Jul;112:30-37. doi: 10.1016/j.fitote.2016.04.019. Epub 2016 Apr 23.
6
Green extraction of grape skin phenolics by using deep eutectic solvents.利用深共晶溶剂进行葡萄皮酚类物质的绿色提取。
Food Chem. 2016 Jun 1;200:159-66. doi: 10.1016/j.foodchem.2016.01.040. Epub 2016 Jan 11.
7
Tailoring properties of natural deep eutectic solvents with water to facilitate their applications.通过与水调配来定制天然低共熔溶剂的性质以促进其应用。
Food Chem. 2015 Nov 15;187:14-9. doi: 10.1016/j.foodchem.2015.03.123. Epub 2015 Apr 3.
8
Applicability evaluation of Deep Eutectic Solvents-Cellulase system for lignocellulose hydrolysis.深共晶溶剂-纤维素酶体系用于木质纤维素水解的适用性评价。
Bioresour Technol. 2015 Apr;181:297-302. doi: 10.1016/j.biortech.2015.01.057. Epub 2015 Jan 28.
9
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Arch Biochem Biophys. 2014 Sep 1;557:18-27. doi: 10.1016/j.abb.2014.05.030. Epub 2014 Jun 11.
10
How polar are choline chloride-based deep eutectic solvents?胆碱氯化物基深共晶溶剂有多极性？
Phys Chem Chem Phys. 2014 Jan 28;16(4):1559-68. doi: 10.1039/c3cp53456a. Epub 2013 Dec 5.
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