Suppr超能文献

表面引导放疗(SGRT)可提高乳腺癌患者摆位准确性。

Surface guided radiotherapy (SGRT) improves breast cancer patient setup accuracy.

机构信息

Department of Hematology, Oncology and Radiation Physics, Skåne University Hospital, Lund, Sweden.

Medical Radiation Physics, Department of Clinical Sciences, Lund University, Lund, Sweden.

出版信息

J Appl Clin Med Phys. 2019 Sep;20(9):61-68. doi: 10.1002/acm2.12700. Epub 2019 Sep 3.

Abstract

PURPOSE

The purpose of the study was to investigate if surface guided radiotherapy (SGRT) can decrease setup deviations for tangential and locoregional breast cancer patients compared to conventional laser-based setup (LBS).

MATERIALS AND METHODS

Both tangential (63 patients) and locoregional (76 patients) breast cancer patients were enrolled in this study. For LBS, the patients were positioned by aligning skin markers to the room lasers. For the surface based setup (SBS), an optical surface scanning system was used for daily setup using both single and three camera systems. To compare the two setup methods, the patient position was evaluated using verification imaging (field images or orthogonal images).

RESULTS

For both tangential and locoregional treatments, SBS decreased the setup deviation significantly compared to LBS (P < 0.01). For patients receiving tangential treatment, 95% of the treatment sessions were within the clinical tolerance of ≤ 4 mm in any direction (lateral, longitudinal or vertical) using SBS, compared to 84% for LBS. Corresponding values for patients receiving locoregional treatment were 70% and 54% for SBS and LBS, respectively. No significant difference was observed comparing the setup result using a single camera system or a three camera system.

CONCLUSIONS

Conventional laser-based setup can with advantage be replaced by surface based setup. Daily SGRT improves patient setup without additional imaging dose to breast cancer patients regardless if a single or three camera system was used.

摘要

目的

本研究旨在探讨与传统基于激光的体位设置(LBS)相比,表面引导放疗(SGRT)是否可以减少切线和局部区域乳腺癌患者的摆位偏差。

材料和方法

本研究纳入了 63 例切线和 76 例局部区域乳腺癌患者。对于 LBS,患者通过将皮肤标记与房间激光对齐进行定位。对于基于表面的设置(SBS),使用光学表面扫描系统使用单相机和三相机系统进行日常设置。为了比较两种设置方法,使用验证成像(场图像或正交图像)评估患者的体位。

结果

对于切线和局部区域治疗,SBS 与 LBS 相比显著降低了摆位偏差(P<0.01)。对于接受切线治疗的患者,95%的治疗疗程在任何方向(横向、纵向或垂直)的临床允许范围内(≤4mm),使用 SBS 为 95%,而使用 LBS 为 84%。对于接受局部区域治疗的患者,SBS 和 LBS 的相应值分别为 70%和 54%。使用单相机系统或三相机系统的设置结果没有观察到显著差异。

结论

传统基于激光的体位设置可以被基于表面的设置取代。每日 SGRT 可改善患者的体位设置,而不会增加乳腺癌患者的额外成像剂量,无论使用单相机系统还是三相机系统。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/91cf/6753725/4b42a883f390/ACM2-20-61-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验