Department of Chemistry, Vali-e-Asr University, Rafsanjan, 77176, Iran.
Mol Divers. 2020 Nov;24(4):1205-1222. doi: 10.1007/s11030-019-09984-x. Epub 2019 Aug 20.
Three-component reaction between arylglyoxals, 1,3-dicetones and enaminoketones leads to new polyfunctionalized tetraone derivatives which may be easily converted to polyfunctionalized pyrroles. Reactions were conducted in water or water-ethanol mixture as green solvents, and all products were isolated by simple washing of the resulting solids with diethyl ether.
芳基乙二醛、1,3-二酮和烯胺酮之间的三组分反应生成了新的多官能化四酮衍生物，这些衍生物可以很容易地转化为多官能化吡咯。反应在水或水-乙醇混合物中进行，作为绿色溶剂，所有产物都通过简单地用二乙醚洗涤所得固体来分离。
