Office of the Director, Bethesda, Maryland.
Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland.
J Infect Dis. 2020 Oct 1;222(9):1432-1434. doi: 10.1093/infdis/jiz442.
This article highlights biomedical research goals for the development of critical tools, including innovative diagnostics, safe and effective vaccines, and new and improved therapeutics, necessary to achieve an end to the global epidemic of sexually transmitted infections. The incidence of sexually transmitted infections (STIs), including gonorrhea, syphilis, chlamydia, and trichomoniasis, is increasing by over 1 million new cases daily and represents a global public health crisis. There is an alarming increase of gonorrhea and syphilis among men who have sex with men and bisexual men, 2 key populations also at high risk for human immunodeficiency virus. A refocused, dedicated, and intensive biomedical research program is needed targeting development of innovative diagnostics, safe and effective vaccines, and new and improved therapeutics. This article highlights biomedical research goals providing critical tools necessary to achieve an end to the global STIs epidemic.
本文强调了为实现性传播感染全球流行终结这一目标而开展生物医学研究的方向，包括开发创新诊断方法、安全有效的疫苗，以及新型和改良疗法。性传播感染（STIs）的发病率（包括淋病、梅毒、衣原体和滴虫病）每天新增超过 100 万例，这构成了全球公共卫生危机。男男性行为者和双性恋男性中淋病和梅毒的发病率呈惊人上升趋势，而这 2 类人群也是艾滋病毒的高危人群。需要重新聚焦、专门和强化生物医学研究方案，以开发创新诊断方法、安全有效的疫苗，以及新型和改良疗法。本文强调了生物医学研究目标，为实现性传播感染全球流行终结提供了必要的关键工具。
