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A step towards a new delimitation of functional somatic syndromes: A latent class analysis of symptoms in a population-based cohort study.迈向新的功能性躯体综合征划分:基于人群队列研究的症状潜在类别分析。
J Psychosom Res. 2018 May;108:102-117. doi: 10.1016/j.jpsychores.2018.03.002. Epub 2018 Mar 9.
2
Environmental Intolerance, Symptoms and Disability Among Fertile-Aged Women.育龄期妇女的环境不耐受、症状和残疾。
Int J Environ Res Public Health. 2018 Feb 8;15(2):293. doi: 10.3390/ijerph15020293.
3
Subjective and objective measures of function and return to work: an observational study with a clinical psychiatric cohort.功能和重返工作的主观和客观测量:一项对临床精神科队列的观察性研究。
Soc Psychiatry Psychiatr Epidemiol. 2018 May;53(5):537-540. doi: 10.1007/s00127-017-1479-5. Epub 2017 Dec 23.
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Prevalence of various environmental intolerances in a Swedish and Finnish general population.瑞典和芬兰普通人群中各种环境不耐受的流行情况。
Environ Res. 2018 Feb;161:220-228. doi: 10.1016/j.envres.2017.11.014.
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Physical, psychological and occupational consequences of job burnout: A systematic review of prospective studies.职业倦怠的身体、心理和职业后果:前瞻性研究的系统综述
PLoS One. 2017 Oct 4;12(10):e0185781. doi: 10.1371/journal.pone.0185781. eCollection 2017.
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Indoor air problems and experiences of injustice in the workplace: A quantitative and a qualitative study.室内空气问题和工作场所的不公正经历:一项定量和定性研究。
Indoor Air. 2018 Jan;28(1):125-134. doi: 10.1111/ina.12409. Epub 2017 Aug 23.
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Core Outcome Domains for Clinical Trials on Somatic Symptom Disorder, Bodily Distress Disorder, and Functional Somatic Syndromes: European Network on Somatic Symptom Disorders Recommendations.躯体症状障碍、躯体形式障碍和功能性躯体综合征临床试验的核心结局领域:躯体症状障碍欧洲网络的建议。
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Differences in psychological and somatic symptom cluster score profiles between subjects with Idiopathic environmental intolerance, major depression and schizophrenia.特发性环境过敏、重度抑郁症和精神分裂症患者心理和躯体症状群评分特征的差异。
Psychiatry Res. 2017 Mar;249:187-194. doi: 10.1016/j.psychres.2016.12.057. Epub 2017 Jan 5.
9
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Experience of living with nonspecific building-related symptoms.与非特异性建筑相关症状共存的经历。
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室内空气相关环境不耐受患者残疾的临床特征

Clinical Characteristics of Disability in Patients with Indoor Air-Related Environmental Intolerance.

作者信息

Vuokko Aki, Karvala Kirsi, Suojalehto Hille, Lindholm Harri, Selinheimo Sanna, Heinonen-Guzejev Marja, Leppämäki Sami, Cederström Sebastian, Hublin Christer, Tuisku Katinka, Sainio Markku

机构信息

Finnish Institute of Occupational Health, Helsinki, Finland.

Nokia Bell Labs, Nokia Group, Espoo, Finland.

出版信息

Saf Health Work. 2019 Sep;10(3):362-369. doi: 10.1016/j.shaw.2019.06.003. Epub 2019 Jun 14.

DOI:10.1016/j.shaw.2019.06.003
PMID:31497334
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6717934/
Abstract

BACKGROUND

Chronic nonspecific symptoms attributed to indoor nonindustrial work environments are common and may cause disability, but the medical nature of this disability is unclear. The aim was to medically characterize the disability manifested by chronic, recurrent symptoms and restrictions to work participation attributed to low-level indoor pollutants at workplace and whether the condition shares features with idiopathic environmental intolerance.

METHODS

We investigated 12 patients with indoor air-related work disability. The examinations included somatic, psychological, and psychiatric evaluations as well as investigations of the autonomic nervous system, cortisol measurements, lung function, and allergy tests. We evaluated well-being, health, disability, insomnia, pain, anxiety, depression, and burnout via questionnaires.

RESULTS

The mean symptom history was 10.5 years; for disabling symptoms, 2.7 years. Eleven patients reported reactions triggered mainly by indoor molds, one by fragrances only. Ten reported sensitivity to odorous chemicals, and three, electric devices. Nearly all had co-occurrent somatic and psychiatric diagnoses and signs of pain, insomnia, burnout, and/or elevated sympathetic responses. Avoiding certain environments had led to restrictions in several life areas. On self-assessment scales, disability showed higher severity and anxiety showed lower severity than in physician assessments.

CONCLUSION

No medical cause was found to explain the disability. Findings support that the condition is a form of idiopathic environmental intolerance and belongs to functional somatic syndromes. Instead of endless avoidance, rehabilitation approaches of functional somatic syndromes are applicable.

摘要

背景

归因于室内非工业工作环境的慢性非特异性症状很常见,可能导致残疾,但这种残疾的医学本质尚不清楚。目的是从医学角度描述由工作场所低水平室内污染物导致的慢性、复发性症状及工作参与受限所表现出的残疾情况,以及该病症是否具有特发性环境不耐受的特征。

方法

我们调查了12名患有与室内空气相关工作残疾的患者。检查包括躯体、心理和精神评估,以及自主神经系统检查、皮质醇测量、肺功能和过敏测试。我们通过问卷调查评估幸福感、健康状况、残疾情况、失眠、疼痛、焦虑、抑郁和倦怠。

结果

平均症状史为10.5年;致残症状的平均症状史为2.7年。11名患者报告反应主要由室内霉菌引发,1名仅由香料引发。10名报告对有气味的化学物质敏感,3名对电子设备敏感。几乎所有人都有同时存在的躯体和精神诊断以及疼痛、失眠、倦怠和/或交感神经反应增强的迹象。避免某些环境导致了几个生活领域的限制。在自我评估量表上,残疾的严重程度高于医生评估,而焦虑的严重程度低于医生评估。

结论

未发现医学原因可解释这种残疾。研究结果支持该病症是特发性环境不耐受的一种形式,属于功能性躯体综合征。适用于功能性躯体综合征的康复方法,而非无休止的回避。