Department of Otolaryngology, Cathay General Hospital, Taipei, Taiwan, ROC.
School of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan, ROC.
Int J Audiol. 2020 Jan;59(1):39-44. doi: 10.1080/14992027.2019.1658907. Epub 2019 Sep 9.
The value of cochlear implantation (CI) has not been established in Taiwan. The purpose of this study was to evaluate the cost-effectiveness of paediatric CI within the context of Taiwan's national health insurance (NHI) programme. A Markov model-based cost-utility analysis (CUA) was conducted to evaluate the cost-effectiveness of a unilateral CI (UCI) with a contralateral acoustic hearing aid (UCI-HA) compared with a bilateral HA. We performed one-way sensitivity analyses to identify the cost variables that affected the incremental cost-effectiveness ratio (ICER) the most. Monte Carlo simulation was used to explore the simultaneous effect of all uncertain parameters on cost-effectiveness. Not applicable. Compared with bilateral HAs, the ICER for UCI-HA was $6487 per quality-adjusted life year (QALY) gained. The ICERs were consistently below $7000 per QALY gained and were most sensitive to the selling price of the external CI device. When this selling price increased by 10%, the ICER of UCI-HA would increase to $6954 per QALY gained. UCI-HA has a probability greater than 50% of being cost-effective if the cost-effectiveness threshold exceeds approximately $10,000 per QALY. Our analysis suggested that within the context of Taiwan's NHI programme, UCI is highly cost-effective for deaf children.
耳蜗植入 (CI) 在台湾的价值尚未得到确立。本研究旨在评估在台湾全民健康保险 (NHI) 计划背景下,儿科 CI 的成本效益。采用基于马尔可夫模型的成本效益分析 (CUA),评估单侧 CI (UCI) 联合对侧声学助听器 (UCI-HA) 与双侧 HA 相比的成本效益。我们进行了单因素敏感性分析,以确定对增量成本效益比 (ICER) 影响最大的成本变量。蒙特卡罗模拟用于探索所有不确定参数对成本效益的综合影响。不适用。与双侧 HA 相比,UCI-HA 的每获得一个质量调整生命年 (QALY) 的增量成本效益比为 6487 美元。ICER 始终低于每获得一个 QALY 的 7000 美元,并且对外部 CI 设备的销售价格最为敏感。当该销售价格上涨 10%时,UCI-HA 的 ICER 将增加到每获得一个 QALY 的 6954 美元。如果成本效益阈值超过每 QALY 约 10,000 美元,UCI-HA 具有超过 50%的成本效益的可能性。我们的分析表明,在台湾 NHI 计划的背景下,UCI 对失聪儿童具有高度的成本效益。