Research Unit for Dietary Studies, The Parker Institute, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.
School of Global Health, University of Copenhagen, Copenhagen, Denmark.
Nutr J. 2019 Sep 10;18(1):56. doi: 10.1186/s12937-019-0478-7.
Several studies have suggested a link between the type of alcoholic beverage consumption and body weight. However, results from longitudinal studies have been inconsistent, and the association between adolescent alcohol consumption long-term weight gain has generally not been examined.
The study was based on data from 720 Danish adolescents aged between 15 to 19 years at baseline from the Danish Youth and Sports Study (YSS). Self-reported alcohol use, height, weight, smoking, social economic status (SES) and physical activity levels were assessed in baseline surveys conducted in 1983 and 1985, and in the follow up survey which was conducted in 2005. Multiple linear regression analyses were used to examine the association between alcohol consumption in adolescence and subsequent weight gain later in midlife.
There was no significant association between total alcohol consumption during adolescence and change in BMI into midlife (P = 0.079) (β - 0.14; 95% CI -0.28, 0.005). Wine consumption was found to be inversely associated to subsequent BMI gain (P = 0.001) (β - 0.46; 95% CI -0.82, - 0.09) while the results were not significant for beer and spirit. The relationship did not differ by gender, but smoking status was found to modify the relationship, and the inverse association between alcohol and BMI gain was seen only among non-smokers (P = 0.01) (β - 0.24; 95% CI -0.41, - 0.06) while no association was found among smokers. Neither adolescent nor attained socioeconomic status in adulthood modified the relationship between alcohol intake and subsequent BMI gain.
Among non-smoking adolescents, consumption of alcohol, and in particular wine, seems to be associated with less weight gain until midlife.
The YSS cohort was retrospectively registered on August 2017. (Study ID number: NCT03244150 ).
多项研究表明,饮酒类型与体重之间存在关联。然而,纵向研究的结果并不一致,青少年饮酒与长期体重增加之间的关联尚未得到普遍研究。
该研究基于丹麦青少年体育研究(YSS)中 720 名年龄在 15 至 19 岁的丹麦青少年在基线时的数据。1983 年和 1985 年进行的基线调查中评估了自我报告的饮酒量、身高、体重、吸烟、社会经济地位(SES)和身体活动水平,而在 2005 年进行的随访调查中评估了这些因素。多线性回归分析用于检验青少年时期的饮酒与中年后体重增加的关系。
青少年时期总饮酒量与中年时 BMI 的变化之间没有显著关联(P=0.079)(β-0.14;95%CI-0.28,0.005)。发现葡萄酒的消费与随后的 BMI 增加呈负相关(P=0.001)(β-0.46;95%CI-0.82,-0.09),而啤酒和烈酒的结果则不显著。该关系不因性别而异,但吸烟状况被发现会改变这种关系,仅在不吸烟者中观察到饮酒与 BMI 增加之间的负相关(P=0.01)(β-0.24;95%CI-0.41,-0.06),而在吸烟者中则没有发现这种关联。青少年时期和成年时期获得的社会经济地位均未改变饮酒与随后 BMI 增加之间的关系。
在不吸烟的青少年中,饮酒,尤其是葡萄酒的消费似乎与中年时体重增加较少有关。
YSS 队列于 2017 年 8 月进行了回顾性注册(研究 ID 号:NCT03244150)。