Dallongeville J, Marécaux N, Ducimetière P, Ferrières J, Arveiler D, Bingham A, Ruidavets J B, Simon C, Amouyel P
INSERM CJF 95-05, Département d'Athérosclérose, Institut Pasteur de Lille, France.
Int J Obes Relat Metab Disord. 1998 Dec;22(12):1178-83. doi: 10.1038/sj.ijo.0800744.
The goal of the present study was to assess the association between alcohol consumption and abdominal fat deposition in France, a country where wine is the most commonly consumed alcoholic beverage.
We analyzed the association between alcohol consumption and various markers of body weight, in a population sample recruited in three distinct geographical areas of France (MONICA centers). This sample included men (n = 1778) and women (n = 1730) aged 35- 64 y, randomly selected from electoral rolls. Alcohol consumption was assessed with a quantitative frequency questionnaire.
Alcohol intake ranged from 0-1655 ml of alcohol per week. Wine was the main source of alcohol, representing 67% of total alcohol intake in both genders. In men, there was no association between alcohol intake and body mass index (BMI) or body weight, whereas in women, alcohol consumption was inversely correlated with BMI (P < 0.0001) and body weight (P < 0.0002). In men, total alcohol consumption was positively associated with waist-to-hip ratio (WHR, P < 0.0002) and waist girth (P < 0.004), independently of BMI. Similarly, in women, positive associations were found between alcohol intake and WHR (P < 0.0001) as well as waist girth (P < 0.0001), independently of BMI. In a linear regression model including types of beverages and usual confounders, reporting consumption of either wine, beer or spirit was poorly associated with WHR in men, whereas wine (P < 0.0008) and beer (P < 0.0001) consumptions were both positively associated with WHR in women. However, there was no evidence of a statistically significant heterogeneous effect of wine, beer and spirits on WHR in both genders.
In a sample of representative French people, in whom wine is the most common alcoholic beverage, alcohol consumption is associated with greater WHR independently of BMI in both men and women.
本研究旨在评估在法国（一个葡萄酒是最常饮用的酒精饮料的国家）酒精消费与腹部脂肪沉积之间的关联。
我们分析了法国三个不同地理区域（莫尼卡中心）招募的人群样本中酒精消费与各种体重指标之间的关联。该样本包括年龄在35至64岁之间的男性（n = 1778）和女性（n = 1730），他们是从选民名单中随机选取的。通过定量频率问卷评估酒精消费情况。
每周酒精摄入量在0至1655毫升之间。葡萄酒是酒精的主要来源，在两性中均占总酒精摄入量的67%。在男性中，酒精摄入量与体重指数（BMI）或体重之间没有关联，而在女性中，酒精消费与BMI（P < 0.0001）和体重（P < 0.0002）呈负相关。在男性中，总酒精消费量与腰臀比（WHR，P < 0.0002）和腰围（P < 0.004）呈正相关，与BMI无关。同样，在女性中，酒精摄入量与WHR（P < 0.0001）以及腰围（P < 0.0001）之间也存在正相关，与BMI无关。在一个包括饮料类型和常见混杂因素的线性回归模型中，报告饮用葡萄酒、啤酒或烈酒与男性的WHR关联较弱，而葡萄酒（P < 0.0008）和啤酒（P < 0.0001）消费在女性中均与WHR呈正相关。然而，没有证据表明葡萄酒、啤酒和烈酒对两性的WHR有统计学上显著的异质效应。
在以葡萄酒为最常见酒精饮料的代表性法国人群样本中，无论男女，酒精消费与更高的WHR相关，且与BMI无关。
