Hydroxide [Ag(OH)L] (L = L, L, L, L), oxide [{AgL}}(μ-O)] (L = L, L, L, L, L) or chloride [AgL]Cl, [Ag(L)]Cl complexes were obtained from reactions of mono- or bicamphorimine derivatives with Ag(OAc) or AgCl. The new complexes were characterized by spectroscopic (NMR, FTIR) and elemental analysis. X-ray photoelectron spectroscopy (XPS), ESI mass spectra and conductivity measurements were undertaken to corroborate formulations. The antimicrobial activity of complexes and some ligands were evaluated towards and , and strains of the bacterial species , , and based on the Minimum Inhibitory Concentrations (MIC). Complexes displayed very high activity against the species studied with the lowest MIC values (3.9 µg/mL) being observed for complexes and against . A significant feature of these redesigned complexes is their ability to sensitize , a trait that was not found for the previously investigated [Ag(NO)L] complexes. The MIC values of the complexes towards bacteria were in the range of those of [Ag(NO)L] and well above those of the precursors Ag(OAc) or AgCl. The activity of the complexes towards normal fibroblasts V79 was evaluated by the MTT (3-[4,5-dimethylthiazol-2-yl]-2,5 diphenyl tetrazolium bromide) assay. Results showed that the complexes have a significant cytotoxicity.