Kingdon Carol, Roberts Devender, Turner Mark A, Storey Claire, Crossland Nicola, Finlayson Kenneth William, Downe Soo
Research in childbirth and health, University of Central Lancashire, Preston, UK
Department of Obstetrics, Liverpool Womens NHS Foundation Trust, Liverpool, UK.
BMJ Open. 2019 Sep 12;9(9):e029672. doi: 10.1136/bmjopen-2019-029672.
To review what is known about the relationship between stillbirth and inequalities from different disciplinary perspectives to inform stillbirth prevention strategies.
Systematic review using the meta-narrative method.
Studies undertaken in the UK.
Scoping phase: experts in field, exploratory electronic searches and handsearching. Systematic searches phase: Nine databases with no geographical or date restrictions. Non-English language studies were excluded.
Any investigation of stillbirth and inequalities with a UK component.
Three authors extracted data and assessed study quality. Data were summarised, tabulated and presented graphically before synthesis of the unfolding storyline by research tradition; and then of the commonalities, differences and interplays between narratives into resultant summary meta-themes.
Fifty-four sources from nine distinctive research traditions were included. The evidence of associations between social inequalities and stillbirth spanned 70 years. Across research traditions, there was recurrent evidence of the social gradient remaining constant or increasing, fuelling repeated calls for action (meta-theme 1: something must be done). There was less evidence of an effective response to these calls. Data pertaining to socioeconomic, area and ethnic disparities were routinely collected, but not consistently recorded, monitored or reported in relation to stillbirth (meta-theme 2: problems of precision). Many studies stressed the interplay of socioeconomic status, deprivation or ethnicity with aggregated factors including heritable, structural, environmental and lifestyle factors (meta-theme 3: moving from associations towards intersectionality and intervention(s)). No intervention studies were identified.
Research investigating inequalities and stillbirth in the UK is underdeveloped. This is despite repeated evidence of an association between stillbirth risk and poverty, and stillbirth risk, poverty and ethnicity. A specific research forum is required to lead the development of research and policy in this area, which can harness the multiple relevant research perspectives and address the intersections between different policy areas.
CRD42017079228.
从不同学科视角回顾关于死产与不平等之间关系的已知情况,以为死产预防策略提供信息。
采用元叙事方法的系统评价。
在英国开展的研究。
范围界定阶段:领域专家、探索性电子检索和手工检索。系统检索阶段:九个无地理或日期限制的数据库。排除非英语语言研究。
任何包含英国部分的关于死产与不平等的调查。
三位作者提取数据并评估研究质量。在按研究传统综合展开的故事情节之前,数据进行了总结、列表并以图表形式呈现;然后将叙述之间的共性、差异和相互作用综合为最终的总结性元主题。
纳入了来自九种不同研究传统的54个来源。社会不平等与死产之间关联的证据跨越70年。在各种研究传统中,反复有证据表明社会梯度保持不变或增加,促使人们反复呼吁采取行动(元主题1:必须有所作为)。对这些呼吁做出有效回应的证据较少。与社会经济、地区和种族差异相关的数据通常会收集,但在死产方面并未始终一致地记录、监测或报告(元主题2:精确性问题)。许多研究强调社会经济地位、贫困或种族与包括遗传、结构、环境和生活方式因素在内的综合因素之间的相互作用(元主题3:从关联走向交叉性和干预)。未识别出干预研究。
在英国,调查不平等与死产的研究尚不发达。尽管反复有证据表明死产风险与贫困、死产风险、贫困和种族之间存在关联,但情况依然如此。需要一个特定的研究论坛来引领该领域研究和政策的发展,该论坛可以利用多个相关研究视角并解决不同政策领域之间的交叉问题。
PROSPERO注册号:CRD42017079228。