Yan Tai Stomatological Hospital, No. 142 Beida Street Zhifu District, Yantai, 264008, Shandong, China.
BMC Oral Health. 2019 Sep 14;19(1):213. doi: 10.1186/s12903-019-0903-5.
Dental caries and type 1 diabetes are responsible for a large burden of global disease; however, the exact prevalence of dental caries among children and adolescents with type 1 diabetes remains controversial, and no quantitative meta-analysis exists. Thus, we performed a meta-analysis to evaluate the prevalence of dental caries among children and adolescents with type 1 diabetes.
We performed a systematic search strategy using PubMed, EMBASE and China National Knowledge Infrastructure for relevant studies investigating the prevalence of dental caries in children and adolescents with type 1 diabetes from July 1971 until December 2018. The pooled prevalence with 95% confidence intervals (95%CIs) and subgroup analyses were calculated using a random effects model.
After screening 358 non-duplicated articles, a total of 10 articles involving 538 individuals were included. The overall prevalence of dental caries among children and adolescents with type 1 diabetes was 67% (95% CI: 0.56-0.77%; I = 83%). The prevalence was highest in South America (84%) and lowest in diabetic patients with good metabolic control (47%).
The prevalence of dental caries was high among children and adolescents with type 1 diabetes. Screening and preventive treatment should be included in dental clinical routines for diabetic children and adolescents, especially in those with poor metabolic control.
龋齿和 1 型糖尿病在全球疾病负担中占很大比例；然而，1 型糖尿病儿童和青少年龋齿的确切患病率仍存在争议，且尚无定量的荟萃分析。因此，我们进行了一项荟萃分析，以评估 1 型糖尿病儿童和青少年的龋齿患病率。
我们使用 PubMed、EMBASE 和中国国家知识基础设施数据库，对 1971 年 7 月至 2018 年 12 月期间调查 1 型糖尿病儿童和青少年龋齿患病率的相关研究进行了系统的搜索策略。使用随机效应模型计算合并患病率及其 95%置信区间（95%CI）和亚组分析。
经过筛选 358 篇非重复文章，共纳入 10 项涉及 538 人的研究。1 型糖尿病儿童和青少年的龋齿总患病率为 67%（95%CI：0.56-0.77%；I=83%）。南美洲的患病率最高（84%），代谢控制良好的糖尿病患者最低（47%）。
1 型糖尿病儿童和青少年的龋齿患病率较高。对于糖尿病儿童和青少年，尤其是代谢控制不佳者，应在牙科临床常规中纳入筛查和预防治疗。
