Department of Pathology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; Department of Pathology, Netherlands Cancer Institute, Amsterdam, the Netherlands.
Department of Computer Science, Faculty of Science, Vrije Universiteit, Amsterdam, the Netherlands.
Oral Oncol. 2019 Nov;98:8-12. doi: 10.1016/j.oraloncology.2019.09.003. Epub 2019 Sep 12.
In this era of information technology, big data analysis is entering biomedical sciences. But what is big data, where do they come from and what can we do with it? In this commentary, the main sources of big data are explained, especially in (head and neck) oncology. It also touches upon the need to integrate various sources of clinical, pathological and quality-of-life data. It discusses some initiatives in linking of such datasets on a nation-wide scale in the Netherlands. Finally, it touches upon important issues regarding governance, FAIRness of data and the need to bring into place the necessary infrastructures needed to fully exploit the full potential of big data sets in head and neck cancer.
在信息技术时代，大数据分析正在进入生物医学科学领域。但是，什么是大数据，它们来自何处，我们可以用它们做什么？在这篇评论中，解释了大数据的主要来源，特别是（头颈部）肿瘤学。它还涉及到整合各种临床、病理和生活质量数据来源的必要性。讨论了在荷兰全国范围内链接此类数据集的一些举措。最后，还涉及到与治理、数据的 FAIRness 以及需要建立必要的基础设施相关的重要问题，以充分挖掘头颈部癌症大数据集的全部潜力。
