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Modulation of lysophosphatidic acid (LPA) receptor activity: the key to successful neural regeneration?

作者信息

Gross Isabel, Bräuer Anja U

机构信息

Research Group Anatomy, School for Medicine and Health Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.

Research Center for Neurosensory Science, Carl von Ossietzky University Oldenburg, Oldenburg, Germany.

出版信息

Neural Regen Res. 2020 Jan;15(1):53-54. doi: 10.4103/1673-5374.264452.

DOI:10.4103/1673-5374.264452
PMID:31535643
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6862401/
Abstract
摘要

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本文引用的文献

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LPA , LPA , LPA , and LPA receptor expression during mouse brain development.LPA、LPA、LPA 和 LPA 受体在小鼠脑发育过程中的表达。
Dev Dyn. 2019 May;248(5):375-395. doi: 10.1002/dvdy.23. Epub 2019 Mar 27.
2
Plasticity Related Gene 3 (PRG3) overcomes myelin-associated growth inhibition and promotes functional recovery after spinal cord injury.可塑性相关基因3(PRG3)可克服髓磷脂相关的生长抑制并促进脊髓损伤后的功能恢复。
Aging (Albany NY). 2016 Oct 15;8(10):2463-2487. doi: 10.18632/aging.101066.
3
Plasticity-related gene 5 promotes spine formation in murine hippocampal neurons.可塑性相关基因 5 促进小鼠海马神经元的脊柱形成。
J Biol Chem. 2014 Sep 5;289(36):24956-70. doi: 10.1074/jbc.M114.597880. Epub 2014 Jul 29.
4
LPA receptor signaling: pharmacology, physiology, and pathophysiology.溶血磷脂酸受体信号传导:药理学、生理学及病理生理学
J Lipid Res. 2014 Jul;55(7):1192-214. doi: 10.1194/jlr.R046458. Epub 2014 Mar 18.
5
Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes.抗溶血磷脂酸抗体可改善创伤性脑损伤的预后。
J Neuroinflammation. 2014 Feb 27;11:37. doi: 10.1186/1742-2094-11-37.
6
Plasticity-related gene 3 promotes neurite shaft protrusion.可塑性相关基因 3 促进神经突轴突突出。
BMC Neurosci. 2013 Mar 19;14:36. doi: 10.1186/1471-2202-14-36.
7
Fingolimod (FTY720): discovery and development of an oral drug to treat multiple sclerosis.芬戈莫德(FTY720):一种治疗多发性硬化症的口服药物的发现和开发。
Nat Rev Drug Discov. 2010 Nov;9(11):883-97. doi: 10.1038/nrd3248. Epub 2010 Oct 29.
8
Synaptic PRG-1 modulates excitatory transmission via lipid phosphate-mediated signaling.突触PRG-1通过脂质磷酸介导的信号传导调节兴奋性传递。
Cell. 2009 Sep 18;138(6):1222-35. doi: 10.1016/j.cell.2009.06.050.
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10
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