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快速可见及扩展近红外多光谱眼底相机。

Fast visible and extended near-infrared multispectral fundus camera.

机构信息

Universitat Politècnica de Catalunya, Center for Sensors, Instruments and Systems Development (CD6),, Spain.

Instituto de Microcirugía Ocular, Barcelona, Spain.

出版信息

J Biomed Opt. 2019 Sep;24(9):1-7. doi: 10.1117/1.JBO.24.9.096007.

Abstract

We present a multispectral fundus camera that performs fast imaging of the ocular posterior pole in the visible and near-infrared (400 to 1300 nm) wavelengths through 15 spectral bands, using a flashlight source made of light-emitting diodes, and CMOS and InGaAs cameras. We investigate the potential of this system for visualizing occult and overlapping structures of the retina in the unexplored wavelength range beyond 900 nm, in which radiation can penetrate deeper into the tissue. Reflectance values at each pixel are also retrieved from the acquired images in the analyzed spectral range. The available spectroscopic information and the visualization of retinal structures, specifically the choroidal vasculature and drusen-induced retinal pigment epithelium degeneration, which are hardly visible in conventional color fundus images, underline the clinical potential of this system as a new tool for ophthalmic diagnosis.

摘要

我们展示了一种多光谱眼底相机,它使用由发光二极管、CMOS 和 InGaAs 相机组成的闪光灯源,在 15 个光谱波段中快速拍摄眼部后极的可见和近红外(400 至 1300nm)波长的图像。我们研究了该系统在 900nm 以上未探索波长范围内可视化视网膜隐匿和重叠结构的潜力,在该波长范围内,辐射可以更深地穿透组织。还从分析的光谱范围内获取的图像中检索到每个像素的反射值。可用的光谱信息和视网膜结构的可视化,特别是脉络膜血管和由渗出物引起的视网膜色素上皮变性,在常规的彩色眼底图像中几乎不可见,这突显了该系统作为眼科诊断新工具的临床潜力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/322a/6997669/67db634c7ca4/JBO-024-096007-g001.jpg

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