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当代穿透性肾损伤的处理-全国性分析。

Contemporary management of penetrating renal trauma - A national analysis.

机构信息

Division of Trauma, Emergency Surgery & Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States.

Division of Trauma, Emergency Surgery & Surgical Critical Care, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, United States.

出版信息

Injury. 2020 Jan;51(1):32-38. doi: 10.1016/j.injury.2019.09.006. Epub 2019 Sep 11.

Abstract

INTRODUCTION

Indications for nonoperative management (NOM) after penetrating renal injury remain ill-defined. Using a national database, we sought to describe the experience of operative and nonoperative management in the United States and retrospectively examine risk factors for failure of NOM.

MATERIALS AND METHODS

The TQIP database 2010-2016 was used to identify patients with penetrating renal trauma. Outcomes of patients treated with an immediate operation (IO) and NOM are described. Failure of NOM was defined as the need for a renal operation after 4 h from arrival. Univariate then multivariable regression analyses were performed to identify predictors of NOM failure.

RESULTS

Out of 8139 patients with kidney trauma, 1,842 had a penetrating mechanism of injury and were included. Of those, 89% were male, median age was 28 years, and 330 (18%) were offered NOM. Compared to IO, NOM patients were less likely to have gunshot wound (59% vs 89% p < 0.001) or high-grade renal injuries [AAST 4-5] (48% vs 76%, p < 0.001). Lower rates of in-hospital complications and shorter ICU and hospital stays were observed in the NOM group. NOM failed in 26 patients (8%). Independent predictors of NOM failure included a concomitant abdominal injury (OR = 3.99, 95% CI 1.03-23.23, p = 0.044), and every point increase in AAST grade (OR = 2.43, 95% CI 1.27-5.21, p = 0.005).

CONCLUSIONS

NOM is highly successful in selected patients. Concomitant abdominal injuries and higher grade AAST injuries predict NOM failure and should be considered when selecting patients for IO or NOM.

摘要

简介

穿透性肾损伤的非手术治疗(NOM)适应证仍不明确。本研究使用国家数据库,旨在描述美国手术和非手术治疗的经验,并回顾性分析 NOM 失败的危险因素。

材料与方法

使用 TQIP 数据库(2010-2016 年),我们确定了穿透性肾损伤患者。描述了接受即刻手术(IO)和 NOM 治疗的患者的结局。NOM 失败定义为从到达后 4 小时开始需要进行肾手术。采用单因素和多因素回归分析,确定 NOM 失败的预测因素。

结果

在 8139 例肾外伤患者中,有 1842 例患者的损伤机制为穿透性,纳入本研究。其中,89%为男性,中位年龄为 28 岁,330 例(18%)患者接受了 NOM。与 IO 相比,NOM 患者更不可能有枪伤(59% vs. 89%,p<0.001)或高等级肾损伤[AAST 4-5](48% vs. 76%,p<0.001)。NOM 组患者院内并发症发生率较低,ICU 入住时间和住院时间较短。26 例(8%)患者 NOM 失败。NOM 失败的独立预测因素包括合并腹部损伤(OR=3.99,95%CI 1.03-23.23,p=0.044)和 AAST 分级每增加 1 分(OR=2.43,95%CI 1.27-5.21,p=0.005)。

结论

在选择合适的患者时,NOM 非常成功。合并腹部损伤和更高等级的 AAST 损伤预测 NOM 失败,在选择患者进行 IO 或 NOM 时应考虑这些因素。

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