Suppr超能文献

穿透性腹部创伤非手术治疗的结果:一项回顾性研究

Outcomes of Nonoperative Management of Penetrating Abdominal Trauma Injury: A Retrospective Study.

作者信息

Obadiel Yasser A, Albrashi Ali, Allahabi Noman, Sharafaddeen Mutahhar, Ahmed Faisal

机构信息

General Surgery, Al-Thawra Modern General Hospital, Sana'a University, Sana'a, YEM.

Surgery, Faculty of Medicine, 21 September University, Sana'a, YEM.

出版信息

Cureus. 2024 Apr 19;16(4):e58599. doi: 10.7759/cureus.58599. eCollection 2024 Apr.

Abstract

BACKGROUND

The treatment of penetrating abdominal injuries has changed in recent years with more focus on "nonoperative management" (NOM) to avoid unnecessary laparotomies while identifying injuries early. Although the NOM approach is widely used for stab wounds, its effectiveness in managing abdominal gunshot wounds is controversial. NOM of penetrating abdominal injuries is becoming more dependent on hemodynamic stability and improved noninvasive radiological interventions. The role of NOM is significantly underreported and underestimated in developing countries, particularly in fragile and conflict-affected states such as Yemen. The present study aims to evaluate the clinical outcomes of NOM in penetrating abdominal trauma injury patients and identify factors associated with NOM failure in a low-resource setting.

METHODS

A retrospective study from January 2021 to December 2022 including patients diagnosed with penetrating abdominal trauma at the General Military Hospital, Sana'a, Yemen, was conducted. Hemodynamically stable patients without peritonitis or clear indications for immediate laparotomy were candidates for NOM and were included in the study. Patients with blunt abdominal injuries, penetrating wounds outside the abdomen, particularly head injury, eviscerated structures, and gastrointestinal hemorrhage, or those pronounced dead on arrival were excluded. The primary outcome was the success and failure rate of NOM necessitating laparotomy. The secondary outcome was the factors associated with NOM failure.

RESULTS

During the study, 256 patients with penetrating abdominal injury were admitted, with 222 (86.7%) undergoing immediate laparotomy and 34 (13.3%) treated with NOM. The mean age was 27.6±7.4 years. Bump explosions, mostly sharp objects (secondary blast injuries), were the main causes of injury (n=18, 52.9%). Other causes were low-velocity gunshot wounds, stab wound injuries, and shotgun injuries in 14 (41.2%), one (2.9%), and one (2.9%), respectively. The majority of patients (n=25, 55.9%) were admitted within 6-24 hours of the incident. The abdominal computed tomography (CT) scan revealed various injuries in all patients, including hemoperitoneum in 11 (32.4%), pneumoperitoneum in five (14.7%), liver injury in 15 (44.1%), foreign body attached to the wall colon in 23 (67.6%), kidney injury in two (5.9%), and splenic injury in one (2.9%). NOM was successful in 31 (91.2%) patients. NOM failed in three (8.8%). One patient was treated via the laparoscopic procedure, and two patients were treated with laparotomy procedures. Five (14.7%) cases required intensive care unit (ICU) admission, with no deaths or major complications. In univariate analysis, the presence of free intra-abdominal fluid (pneumoperitoneum) on the initial CT scan and the need for ICU admission were associated with NOM failure and were statistically significant (p<0.05).

CONCLUSION

Our findings support that some penetrating abdominal trauma patients can benefit from NOM. The goal of preventing unnecessary laparotomies should be aligned with a comprehensive comprehension of the clinical signs and symptoms of NOM failure and the necessity for surgical intervention. Serial abdominal examinations remain the foundation of selected NOM; nevertheless, radiological and laboratory tests can be important tools in decision-making. In this study, free intra-abdominal fluid on the initial CT scan and the need for ICU admission were associated with NOM failure.

摘要

背景

近年来,穿透性腹部损伤的治疗方式有所改变,更多地聚焦于“非手术治疗”(NOM),以便在早期识别损伤的同时避免不必要的剖腹手术。尽管NOM方法广泛应用于刺伤,但它在处理腹部枪伤方面的有效性仍存在争议。穿透性腹部损伤的NOM越来越依赖于血流动力学稳定性以及改进的非侵入性放射学干预措施。在发展中国家,特别是在也门等脆弱和受冲突影响的国家,NOM的作用被严重低估和报道不足。本研究旨在评估NOM在穿透性腹部创伤患者中的临床结局,并确定在资源匮乏环境下与NOM失败相关的因素。

方法

对2021年1月至2022年12月期间在也门萨那总医院被诊断为穿透性腹部创伤的患者进行了一项回顾性研究。血流动力学稳定、无腹膜炎或无立即剖腹手术明确指征的患者为NOM的候选对象,并被纳入研究。排除腹部钝性损伤、腹部以外的穿透伤,特别是头部损伤、脏器脱出、胃肠道出血或到达时已宣告死亡的患者。主要结局是NOM后需要剖腹手术的成功率和失败率。次要结局是与NOM失败相关的因素。

结果

在研究期间,256例穿透性腹部损伤患者入院,其中222例(86.7%)立即接受了剖腹手术,34例(13.3%)接受了NOM治疗。平均年龄为27.6±7.4岁。撞击爆炸,主要是尖锐物体(二次爆炸伤),是主要的致伤原因(n = 18,52.9%)。其他原因分别为低速枪伤、刺伤和霰弹枪伤,各有14例(41.2%)、1例(2.9%)和1例(2.9%)。大多数患者(n = 25,55.9%)在事件发生后6 - 24小时内入院。腹部计算机断层扫描(CT)显示所有患者均有不同程度的损伤,包括腹腔积血11例(32.4%)、气腹5例(14.7%)肝损伤15例(44.1%)结肠壁附着异物23例(67.6%)、肾损伤2例(5.9%)和脾损伤1例(2.9%)。31例(91.2%)患者NOM成功。3例(8.8%)NOM失败。1例患者通过腹腔镜手术治疗,2例患者接受剖腹手术治疗。5例(14.7%)患者需要入住重症监护病房(ICU),无死亡或严重并发症。在单因素分析中,初始CT扫描显示腹腔内有游离液体(气腹)以及需要入住ICU与NOM失败相关,且具有统计学意义(p < 0.05)。

结论

我们的研究结果支持部分穿透性腹部创伤患者可从NOM中获益。预防不必要剖腹手术的目标应与对NOM失败的临床体征和症状以及手术干预必要性的全面理解相一致。系列腹部检查仍然是选定的NOM的基础;然而,放射学和实验室检查可能是决策中的重要工具。在本研究中,初始CT扫描显示腹腔内有游离液体以及需要入住ICU与NOM失败相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1f71/11102771/2a3128314fde/cureus-0016-00000058599-i01.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验