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多发伤和/或重伤患者泌尿生殖道损伤的初始手术处理:系统评价与临床实践指南更新

Initial surgical management of injuries to the urogenital tract in patients with polytrauma and/or severe injuries: a systematic review and clinical practice guideline update.

作者信息

Ruf Christian, Kluth Luis, Wahlen Sarah, Breuing Jessica, Nestler Tim

机构信息

Department of Urology, Bundeswehr Hospital of Ulm, Ulm, Germany.

Department of Urology, University Hospital, Goethe University of Frankfurt, Frankfurt Am Main, Germany.

出版信息

Eur J Trauma Emerg Surg. 2025 Apr 29;51(1):182. doi: 10.1007/s00068-025-02847-1.

Abstract

PURPOSE

Our aim was to update evidence-based and consensus-based recommendations for the initial surgical management of urogenital injuries in patients with polytrauma and/or severe injuries based on current evidence. This guideline topic is part of the 2022 update of the German Guideline on the Treatment of Patients with Polytrauma and/or Severe Injuries.

METHODS

MEDLINE and Embase were systematically searched to June 2021. Randomised controlled trials, prospective cohort studies, and comparative registry studies were included if they compared surgical and/or therapeutic interventions for urogenital injuries in the hospital setting. We considered patient-relevant clinical outcomes such as mortality and bleeding control, or coagulation parameters as surrogate outcomes. Risk of bias was assessed using NICE 2012 checklists. The evidence was synthesised narratively, and expert consensus was used to develop recommendations and determine their strength.

RESULTS

Two new studies were identified. The topics covered were the comparison of outcomes after surgical and nonsurgical management as well as the use of surgical repair versus catheter drainage in patients with extraperitoneal bladder injuries. Three recommendations were modified, one of which for editorial reasons. All achieved strong consensus.

CONCLUSION

The following key recommendations are made. 1. Renal artery injuries can be managed using an endovascular approach. 2. Depending on the type and severity of the injury and concomitant injuries, renal injuries should be managed with the intent to preserve the organ. 3. Extraperitoneal bladder ruptures without involvement of the bladder neck should be conservatively treated with catheterisation.

摘要

目的

我们的目标是根据当前证据,更新基于循证和共识的关于多发伤和/或重伤患者泌尿生殖系统损伤初始手术管理的建议。本指南主题是《德国多发伤和/或重伤患者治疗指南》2022年更新内容的一部分。

方法

系统检索至2021年6月的MEDLINE和Embase数据库。纳入随机对照试验、前瞻性队列研究和比较登记研究,前提是这些研究比较了医院环境中泌尿生殖系统损伤的手术和/或治疗干预措施。我们将与患者相关的临床结局(如死亡率和出血控制)或凝血参数视为替代结局。使用英国国家卫生与临床优化研究所(NICE)2012年清单评估偏倚风险。对证据进行叙述性综合,并利用专家共识制定建议并确定其强度。

结果

确定了两项新研究。涵盖的主题包括手术和非手术管理后的结局比较,以及腹膜外膀胱损伤患者手术修复与导管引流的使用。三项建议进行了修改,其中一项是出于编辑原因。所有建议均达成了强烈共识。

结论

提出以下关键建议。1. 肾动脉损伤可采用血管内方法处理。2. 根据损伤类型和严重程度以及伴随损伤情况,肾损伤的处理应旨在保留器官。3. 未累及膀胱颈的腹膜外膀胱破裂应采用导尿保守治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e648/12037646/c4400168fd00/68_2025_2847_Fig1_HTML.jpg

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