Department of Preventive Intervention for Psychiatric Disorders, National Institute of Mental Health, National Center of Neurology and Psychiatry, 4-1-1 Ogawahigashi, Kodaira, Tokyo 187-8553, Japan; Stockholm Center for Health and Social Change (SCOHOST), Södertörn University, Huddinge 141 89, Sweden.
Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, Barcelona, Spain; ICREA, Pg. Lluis Companys 23, Barcelona, Spain.
J Affect Disord. 2020 Jan 1;260:604-609. doi: 10.1016/j.jad.2019.09.042. Epub 2019 Sep 9.
As yet, there has been little research on the association between physical multimorbidity (the co-occurrence of two or more physical illnesses) and suicide, and results have been mixed. This study examined if physical multimorbidity is associated with suicidal behavior in the general population in the United States.
Data were analyzed from 15,311 adults that were obtained from the Collaborative Psychiatric Epidemiology Surveys (CPES). Information was obtained on nine self-reported physical health conditions and lifetime suicidal behavior (suicidal ideation, plan, and attempts). Logistic regression analysis was used to examine associations.
An increasing number of physical health conditions was associated with higher odds for suicidal behavior. Compared to those with no physical conditions, individuals with ≥ 4 physical illnesses had 2.99, 4.82, and 4.39 times higher odds for reporting suicidal ideation, a suicide plan, and suicide attempts, respectively. An interaction analysis showed that for suicide attempts the association was stronger in younger rather than older adults.
The data were cross-sectional and information on physical conditions and suicidal behavior was self-reported and may have been subject to reporting bias.
As multimorbidity has increased in recent decades in the United States, alerting medical practitioners to the increased risk of suicidal behavior in adults who have multiple medical conditions as well as screening for suicidality in this group may be important preventive measures to help reduce suicidal behavior in the general population.
目前,关于身体多病(两种或多种身体疾病同时存在)与自杀之间的关联的研究甚少,结果也不一致。本研究在美国一般人群中检验了身体多病是否与自杀行为有关。
从协作精神流行病学调查(CPES)中获得了 15311 名成年人的数据。调查获得了 9 种自我报告的身体健康状况和终生自杀行为(自杀意念、计划和尝试)的信息。使用逻辑回归分析来检验关联。
身体疾病数量的增加与自杀行为的可能性增加相关。与没有身体疾病的人相比,患有≥4 种身体疾病的个体报告自杀意念、自杀计划和自杀尝试的可能性分别高出 2.99、4.82 和 4.39 倍。交互分析显示,对于自杀尝试,这种关联在年轻人中比在老年人中更强。
数据为横断面,身体状况和自杀行为的信息为自我报告,可能存在报告偏倚。
在美国,近年来多病的情况有所增加,提醒医疗保健提供者注意患有多种疾病的成年人自杀行为风险增加,并对该人群进行自杀倾向筛查,可能是减少一般人群自杀行为的重要预防措施。