产生粒细胞集落刺激因子的膀胱癌

Morinaga Ryota, Kawahara Takashi, Kuroda Shinnosuke, Inayama Yoshiaki, Uemura Hiroji

Departments of Urology and Renal Transplantation, Yokohama City University Medical Center, Yokohama, Japan.

Division of Diagnostic Pathology, Yokohama City University Medical Center, Yokohama, Japan.

Case Rep Oncol. 2019 Aug 6;12(2):603-607. doi: 10.1159/000502174. eCollection 2019 May-Aug.

Granulocyte colony-stimulating factor (G-CSF)-producing bladder cancer is rare, with only 75 cases reported in Japan. A 67-year-old woman was referred to our institution for the further examination of gross hematuria. Cystoscopy revealed a 7-cm bladder tumor. The initial white blood cell count was 17,100/μL, and a transurethral resected specimen showed G-CSF expression. CT revealed that the tumor had invaded the colon. As the patient had uncontrollable schizophrenia, radical cystectomy was abandoned. We herein report a case of G-CSF-producing bladder tumor.

产生粒细胞集落刺激因子（G-CSF）的膀胱癌很罕见，日本仅报告过75例。一名67岁女性因肉眼血尿被转诊至我院做进一步检查。膀胱镜检查发现一个7厘米的膀胱肿瘤。初始白细胞计数为17,100/μL，经尿道切除的标本显示有G-CSF表达。CT显示肿瘤已侵犯结肠。由于患者患有无法控制的精神分裂症，放弃了根治性膀胱切除术。我们在此报告一例产生G-CSF的膀胱肿瘤病例。