Xia Rui, Qiu Pingting, Lin Huiying, Ye Bingzhao, Wan Mingyue, Li Moyi, Tao Jing, Chen Lidian, Zheng Guohua
College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, China.
Department of Rehabilitation, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Front Psychol. 2019 Sep 10;10:2075. doi: 10.3389/fpsyg.2019.02075. eCollection 2019.
A growing number of studies have shown that mind-body exercise is beneficial to cognitive function, especially memory, in elderly MCI patients. However, few studies have explored the effect of mind-body exercise on the attention of MCI population. We recruited 69 participants and divided them equally into Baduanjin, brisk walking (BWK) exercise or usual physical activity (UAP) control groups. The two exercise groups performed 60 min of exercise three times per week for 24 weeks. All subjects underwent whole-brain functional MRI and assessment of attentional abilities, including selective, divided, and sustained attention, and processing speed at baseline and after 24 weeks. The results show that: Baduanjin exercise significantly increased the selective attention of MCI patients, and Dorsal attention network (DAN) of Baduanjin exercise group exhibited functional connectivity decreased in right rolandic operculum (ROL. R), right middle temporal gyrus (MTG. R), right supramarginal inferior parietal, angular gyri (IPL. R), right precuneus (PCUN. R), and right fusiform gyrus (FFG. R) regions compared with the other two groups. The BWK exercise group had obviously functional connectivity increased in IPL. R and decreased in the MTG. R region compared to that in the UAP group. But no significant association between the changes of functional connectivity of DAN and the change of attentional ability test was observed. Thus, our data indicated Baduanjin exercise may be a potential beneficial intervention to improve the attention of the elderly with MCI. Further study with more samples is necessary to elucidate its imaging mechanism.
越来越多的研究表明，身心锻炼对老年轻度认知障碍（MCI）患者的认知功能，尤其是记忆力有益。然而，很少有研究探讨身心锻炼对MCI人群注意力的影响。我们招募了69名参与者，并将他们平均分为八段锦组、快走（BWK）锻炼组或常规体育活动（UAP）对照组。两个锻炼组每周进行3次60分钟的锻炼，持续24周。所有受试者在基线时和24周后均接受了全脑功能磁共振成像以及注意力能力评估，包括选择性、分散性和持续性注意力，以及处理速度。结果显示：八段锦锻炼显著提高了MCI患者的选择性注意力，与其他两组相比，八段锦锻炼组的背侧注意力网络（DAN）在右侧额下回（ROL.R）、右侧颞中回（MTG.R）、右侧顶下小叶、角回（IPL.R）、右侧楔前叶（PCUN.R）和右侧梭状回（FFG.R）区域的功能连接性降低。与UAP组相比，BWK锻炼组在IPL.R区域的功能连接性明显增加，而在MTG.R区域降低。但未观察到DAN功能连接性变化与注意力能力测试变化之间存在显著关联。因此，我们的数据表明八段锦锻炼可能是改善老年MCI患者注意力的一种潜在有益干预措施。需要更多样本的进一步研究来阐明其成像机制。
