表观遗传学与女性生殖衰老
Epigenetics and Female Reproductive Aging.
作者信息
Chamani Isaac J, Keefe David L
机构信息
NYU School of Medicine, New York, NY, United States.
Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, United States.
出版信息
Front Endocrinol (Lausanne). 2019 Aug 29;10:473. doi: 10.3389/fendo.2019.00473. eCollection 2019.
Abstract
With more women than ever waiting until a more advanced age to have children, there exists a newfound urgency to identify the various implications aging has on human reproduction, and understand the disrupted biological processes that result in these changes. In this review, we focus on one recent area of study: the age related epigenetic changes that have been found in female reproductive organs, and the effect these changes may contribute to reproductive outcomes.
摘要
随着越来越多的女性推迟生育年龄，确定衰老对人类生殖的各种影响以及了解导致这些变化的生物过程紊乱变得愈发紧迫。在本综述中，我们聚焦于一个最新的研究领域：在女性生殖器官中发现的与年龄相关的表观遗传变化，以及这些变化可能对生殖结果产生的影响。
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