Department of Chemistry, Missouri University of Science and Technology, Rolla, MO 65409, USA.
Nanoscale. 2019 Oct 10;11(39):18026-18030. doi: 10.1039/c9nr05047g.
We present the pH-triggered reversible assembly of DNA origami clusters in a stepwise fashion. The structure formation and dissociation are controlled by a series of consecutive pH-stimulation processes that rely on the triplex-to-duplex transition of DNA triplexes in different pH conditions. This multilevel dynamic assembly strategy brings more structural complexity and provides the possibility of developing intelligent materials for engineering applications.
我们提出了 DNA 折纸结构簇的 pH 触发的逐步可逆组装。结构的形成和解离由一系列连续的 pH 刺激过程控制，这些过程依赖于不同 pH 条件下 DNA 三链体的三聚体-双链体的转变。这种多层次的动态组装策略带来了更多的结构复杂性，并为工程应用的智能材料的发展提供了可能性。
