Öztekin Ünal, Caniklioğlu Mehmet, Sarı Sercan, Selmi Volkan, Gürel Abdullah, Caniklioğlu Ayşen, Işıkay Levent
Urology, Bozok University Faculty of Medicine, Yozgat, TUR.
Biochemistry, Bozok University Faculty of Medicine, Yozgat, TUR.
Cureus. 2019 Jul 25;11(7):e5242. doi: 10.7759/cureus.5242.
Objective The aim of this study is to determine the relationship between neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), and red blood cell distribution width (RDW)/platelet ratio (RPR) values, which are pro-inflammatory markers, with abnormal sperm parameters, and to evaluate their availability as predictive markers. Materials and methods A total of 160 patients, 80 of whom were the control group, formed with match-pair analysis (Group 1), and 80 patients with abnormal sperm analysis, who met the study criteria (Group 2), were included in the study. Complete blood count results were recorded. NLR, PLR, and RPR values were calculated using hematological parameters, and a comparison was made between the two groups. Results The mean age was 31.23 ± 5.1 years in Group 1 and 31.33 ± 6.4 years in Group 2. NLR values were 1.84 ± 0.57-1.87 ± 0.65 (P =0.77), PLR values were 105.42 ± 23.89-111.42 ± 34.54 (P = 0.62) and RPR values were 0.05 ± 0.009-0.05 ± 0.01 (P =0.45), respectively. There was no statistically significant difference between the groups. Conclusions We investigated whether NLR, PLR, and RPR results can be used as a predictive marker on abnormal sperm parameters. We do not recommend the use of these parameters as a predictive marker.
目的 本研究旨在确定作为促炎标志物的中性粒细胞/淋巴细胞比值(NLR)、血小板/淋巴细胞比值(PLR)以及红细胞分布宽度(RDW)/血小板比值(RPR)与异常精子参数之间的关系,并评估它们作为预测标志物的可用性。材料与方法 本研究共纳入160例患者,其中80例通过配对分析组成对照组(第1组),另外80例符合研究标准的精子分析异常患者(第2组)。记录全血细胞计数结果。使用血液学参数计算NLR、PLR和RPR值,并对两组进行比较。结果 第1组的平均年龄为31.23±5.1岁,第2组为31.33±6.4岁。NLR值分别为1.84±0.57 - 1.87±0.65(P = 0.77),PLR值分别为105.42±23.89 - 111.42±34.54(P = 0.62),RPR值分别为0.05±0.009 - 0.05±0.01(P = 0.45)。两组之间无统计学显著差异。结论 我们研究了NLR、PLR和RPR结果是否可作为异常精子参数的预测标志物。我们不建议将这些参数用作预测标志物。