Aykan Serdar, Canat Lütfi, Gönültaş Serkan, Atalay Hasan Anıl, Altunrende Fatih
Department of Urology, Bağcılar Training and Research Hospital, Istanbul, Turkey.
Department of Urology, Okmeydanı Training and Research Hospital, Istanbul, Turkey.
World J Mens Health. 2017 Apr;35(1):51-56. doi: 10.5534/wjmh.2017.35.1.51.
The aim of this study was to evaluate the relationship of seminal parameters with the neutrophil-to-lymphocyte ratio (NLR) and the platelet-to-lymphocyte ratio (PLR), which are inflammatory markers, in men with an abnormal semen analysis and men with normozoospermia.
Fifty-seven men with abnormal semen analyses and 59 men with normozoospermia were included in this cross-sectional study. A complete blood count was recorded, and the NLR and PLR were calculated from the hematologic parameters.
The NLR was 1.84±0.78 in the normozoospermic group and 1.80±0.75 in the abnormal semen analysis group. The PLR was 95.32±35.47 in the normozoospermic group and 93.57±28.09 in the abnormal semen analysis group. No significant differences were found between the normozoospermic and the abnormal semen analysis group in the NLR (p=0.828) or the PLR (p=0.768). In addition, no seminal parameters were correlated with the NLR or the PLR (p>0.05).
We do not recommend using the NLR or the PLR as markers to screen for abnormal semen parameters or male infertility.
本研究旨在评估精液分析异常男性和精子正常男性的精液参数与炎症标志物中性粒细胞与淋巴细胞比值（NLR）及血小板与淋巴细胞比值（PLR）之间的关系。
本横断面研究纳入了57例精液分析异常的男性和59例精子正常的男性。记录全血细胞计数，并根据血液学参数计算NLR和PLR。
精子正常组的NLR为1.84±0.78，精液分析异常组为1.80±0.75。精子正常组的PLR为95.32±35.47，精液分析异常组为93.57±28.09。精子正常组与精液分析异常组在NLR（p = 0.828）或PLR（p = 0.768）方面未发现显著差异。此外，精液参数与NLR或PLR均无相关性（p>0.05）。
我们不建议将NLR或PLR用作筛查精液参数异常或男性不育的标志物。
