Madhusudhana Sresty N V N, Raju A Krishnam, Reddy B Nagarjuna, Sahithya V C, Mohmd Yakub, Kumar G Deleep, Kumar T Anil, Rushdi Tasneem, Aparna S, Prasad G Durga, Bajwa Harjot Kaur
Department of Radiotherapy, Basavatarakam Indo American Cancer Hospital and Research Institute, Hyderabad, Telangana, India.
Department of Radiotherapy, Government Medical College and General Hospital, Anantapuramu, Andhra Pradesh, India.
J Med Phys. 2019 Jul-Sep;44(3):222-227. doi: 10.4103/jmp.JMP_11_19.
TomoTherapy is a modern radiation treatment technique in which intensity-modulated radiation therapy (IMRT) is delivered in helical fashion. A two-dimensional (2D) array which has been existing for IMRT patient-specific quality assurance (PSQA) verifications for many years is I'MatriXX. Our objectives were to validate this I'MatriXX and to evaluate it for different patient sites and fractionation schedules of TomoTherapy treatment. Twenty-five plans were created with virtual target for different possible pitch values and field widths for validation. Gamma index criteria of 3%/2% dose differences and 3/2 mm distance to agreement were used. QA plans of 26 different treatment sites and different fractionation schedules were used. Results indicated that the matrix response is independent of field width, pitch, and modulation factor of TomoTherapy with 3%, 3 mm criteria. High passing rate ranging from 99.7% to 90.7% was observed for selected patient plans. We found that I'MatriXX 2D array can be utilized for easy and quick TomoTherapy PSQA.
螺旋断层放疗是一种现代放射治疗技术，它以螺旋方式进行调强放射治疗（IMRT）。多年来一直用于IMRT患者特异性质量保证（PSQA）验证的二维（2D）阵列是I'MatriXX。我们的目标是验证该I'MatriXX，并针对螺旋断层放疗治疗的不同患者部位和分割方案对其进行评估。通过虚拟靶标创建了25个计划，用于验证不同的可能螺距值和射野宽度。使用了3%/2%剂量差异和3/2毫米距离一致性的伽马指数标准。使用了26个不同治疗部位和不同分割方案的QA计划。结果表明，在3%、3毫米标准下，矩阵响应与螺旋断层放疗的射野宽度、螺距和调制因子无关。对于选定的患者计划，观察到较高的通过率，范围从99.7%到90.7%。我们发现I'MatriXX二维阵列可用于简便快速的螺旋断层放疗PSQA。
